Gene · 4172
MCM3: minichromosome maintenance complex component 3
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MCM3: minichromosome maintenance complex component 3. Genes, record 4172. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4172
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P25205 | DNA replication licensing factor MCM3 | 808 | 28 | Ensembl, GeneID, HGNC |
Source UniProt
Patents57
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 18019 | P25205 | Espacenet |
| WO 2025163163 A1 | 2025-08-07 | 2 | P25205 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 18019 | P25205 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 7010 | P25205 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 51680 | P25205 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 154651 | P25205 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 1427 | P25205 | Espacenet |
| US 10501513 B2 | 2019-12-10 | 7010 | P25205 | Espacenet |
| US 10094826 B2 | 2018-10-09 | 5 | P25205 | Espacenet |
| JP 2018138044 A | 2018-09-06 | 137 | P25205 | Espacenet |
1 to 10 of 57
See all 57 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,296
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MCM3 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 16 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 11 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 8 | 2025 |
| P30CA014051 | Cancer Center Support (Core) Grant | 8 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 7 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 6 | 2025 |
| R01GM045436 | Initiation of DNA Replication at Cell Origins in Yeast | 6 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 5 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 5 | 2025 |
| R01GM081648 | Single-molecule visualization of transcription regulation mechanisms | 5 | 2025 |
1 to 10 of 1,296Source NIH's project files
See all 1,296 nih grantsPapers2,183
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Conformational switching and spatial heterogeneity: Decoding SERPINE1/PAI-1as a multifaceted driver of tumor progression and therapy resistance. | Crit Rev Oncol Hematol | 2026 | 42826913 | PubTator, text mining | PubMed |
| Evaluating MCM3 Expression as a Diagnostic and Prognostic Marker in Oral Epithelial Dysplasia and OSCC: A Systematic Review. | J Maxillofac Oral Surg | 2026 | 42824588 | PubTator, text mining | PubMed |
| Circular RNA MCM3 recruits USP49 to stabilize PTBP1 and promote cisplatin resistance in cervical squamous cell carcinoma. | Oncogene | 2026 | 42728347 | PubTator, text mining | PubMed |
| A systems biology approach to find representative genes in Acute Myeloid Leukemia. | PLoS One | 2026 | 42507679 | PubTator, text mining | PubMed |
| Establishing bone tissue level changes associated with cognitive impairment. | J Gerontol A Biol Sci Med Sci | 2026 | 42172587 | PubTator, text mining | PubMed |
| Distinct roles of MCM2-7 subunits in replication licensing in human cells. | Nat Commun | 2026 | 42151158 | PubTator, text mining | PubMed |
| E2F Accelerates the Proliferation of B-Cell Non-Hodgkin Lymphomas by Upregulating Cell-Cycle Genes. | Curr Med Sci | 2026 | 42043646 | PubTator, text mining | PubMed |
| Cross-species single-cell transcriptomic analyses reveal evolutionary conservation and diversification of ovarian tissues. | J Anim Sci Biotechnol | 2026 | 41975518 | PubTator, text mining | PubMed |
| Acute E-Cigarette Aerosol Condensate Exposure Disrupts the Transcriptome and Proteome Profiles of Human Bronchial Epithelial BEAS-2B Cells. | Cells | 2026 | 41892316 | PubTator, text mining | PubMed |
| Mechanism of Anticancer Activity of Cedrol in Epidermal Carcinoma Cells and Its Validation in 3D Artificial Skin Model. | J Microbiol Biotechnol | 2026 | 41881674 | PubTator, text mining | PubMed |
1 to 10 of 2,183
See all 2,183 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4172
GET https://conductscience.org/api/genes/v1/4172/patents?page=2