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Gene · 4172

MCM3: minichromosome maintenance complex component 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MCM3: minichromosome maintenance complex component 3. Genes, record 4172. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4172

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Gene

Symbol
MCM3
HGNC
Name
minichromosome maintenance complex component 3
HGNC
NCBI Gene ID
4172
NCBI Gene
HGNC ID
HGNC:6945
HGNC
Ensembl
ENSG00000112118
NCBI Gene
Aliases
HCC5, P1-MCM3, P1.h, RLFB
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P25205DNA replication licensing factor MCM380828Ensembl, GeneID, HGNC

Source UniProt

Patents57

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1918019P25205Espacenet
WO 2025163163 A12025-08-072P25205Espacenet
JP 2025517970 A2025-06-1218019P25205Espacenet
JP 2024123008 A2024-09-107010P25205Espacenet
US 11446398 B22022-09-2051680P25205Espacenet
JP 2022524081 A2022-04-27154651P25205Espacenet
WO 2020043864 A12020-03-051427P25205Espacenet
US 10501513 B22019-12-107010P25205Espacenet
US 10094826 B22018-10-095P25205Espacenet
JP 2018138044 A2018-09-06137P25205Espacenet

1 to 10 of 57

See all 57 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,296

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMCM3 papersNewest fiscal year
P30CA008748Cancer Center Support Grant162025
P30CA016672Cancer Center Support Grant112025
P01CA013106Targeting Transcription and Splicing in Cancer82025
P30CA014051Cancer Center Support (Core) Grant82025
P30CA016086Cancer Center Support Grant72025
P30CA010815Consolidated Basic Cancer Research Program62025
R01GM045436Initiation of DNA Replication at Cell Origins in Yeast62025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant52025
P30CA016056Roswell Park Cancer Center Support Grant52025
R01GM081648Single-molecule visualization of transcription regulation mechanisms52025

1 to 10 of 1,296Source NIH's project files

See all 1,296 nih grants

Papers2,183

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Conformational switching and spatial heterogeneity: Decoding SERPINE1/PAI-1as a multifaceted driver of tumor progression and therapy resistance.Crit Rev Oncol Hematol202642826913PubTator, text miningPubMed
Evaluating MCM3 Expression as a Diagnostic and Prognostic Marker in Oral Epithelial Dysplasia and OSCC: A Systematic Review.J Maxillofac Oral Surg202642824588PubTator, text miningPubMed
Circular RNA MCM3 recruits USP49 to stabilize PTBP1 and promote cisplatin resistance in cervical squamous cell carcinoma.Oncogene202642728347PubTator, text miningPubMed
A systems biology approach to find representative genes in Acute Myeloid Leukemia.PLoS One202642507679PubTator, text miningPubMed
Establishing bone tissue level changes associated with cognitive impairment.J Gerontol A Biol Sci Med Sci202642172587PubTator, text miningPubMed
Distinct roles of MCM2-7 subunits in replication licensing in human cells.Nat Commun202642151158PubTator, text miningPubMed
E2F Accelerates the Proliferation of B-Cell Non-Hodgkin Lymphomas by Upregulating Cell-Cycle Genes.Curr Med Sci202642043646PubTator, text miningPubMed
Cross-species single-cell transcriptomic analyses reveal evolutionary conservation and diversification of ovarian tissues.J Anim Sci Biotechnol202641975518PubTator, text miningPubMed
Acute E-Cigarette Aerosol Condensate Exposure Disrupts the Transcriptome and Proteome Profiles of Human Bronchial Epithelial BEAS-2B Cells.Cells202641892316PubTator, text miningPubMed
Mechanism of Anticancer Activity of Cedrol in Epidermal Carcinoma Cells and Its Validation in 3D Artificial Skin Model.J Microbiol Biotechnol202641881674PubTator, text miningPubMed

1 to 10 of 2,183

See all 2,183 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4172

GET https://conductscience.org/api/genes/v1/4172/patents?page=2