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Gene · 4175

MCM6: minichromosome maintenance complex component 6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MCM6: minichromosome maintenance complex component 6. Genes, record 4175. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4175

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Gene

Symbol
MCM6
HGNC
Name
minichromosome maintenance complex component 6
HGNC
NCBI Gene ID
4175
NCBI Gene
HGNC ID
HGNC:6949
HGNC
Ensembl
ENSG00000076003
NCBI Gene
Aliases
MCG40308, Mis5, P105MCM
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q14566DNA replication licensing factor MCM682130Ensembl, GeneID, HGNC

Source UniProt

Patents82

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026063308 A2026-03-2625Q14566Espacenet
JP 2026004568 A2026-01-1453626Q14566Espacenet
EP 4650780 A22025-11-192307Q14566Espacenet
EP 4641201 A22025-10-291871Q14566Espacenet
WO 2025163163 A12025-08-075Q14566Espacenet
JP 2025517969 A2025-06-121871Q14566Espacenet
JP 2025517970 A2025-06-122307Q14566Espacenet
US 11446398 B22022-09-2051701Q14566Espacenet
JP 2022524081 A2022-04-27154672Q14566Espacenet
US 11078247 B22021-08-036671Q14566Espacenet

1 to 10 of 82

See all 82 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,387

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMCM6 papersNewest fiscal year
P30CA008748Cancer Center Support Grant172025
P30CA016672Cancer Center Support Grant122025
P30CA014051Cancer Center Support (Core) Grant112025
P01CA013106Targeting Transcription and Splicing in Cancer82025
R01GM045436Initiation of DNA Replication at Cell Origins in Yeast82025
P30CA045508CSHL Cancer Center Support Grant52025
R01GM081648Single-molecule visualization of transcription regulation mechanisms52025
P30CA015704Cancer Center Support Grant42025
P30CA016056Roswell Park Cancer Center Support Grant42025
P30CA046934University of Colorado Cancer Center Support Grant42025

1 to 10 of 1,387Source NIH's project files

See all 1,387 nih grants

Papers2,153

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Multi-omics analyses prioritize potential biomarkers and drug targets for obstructive sleep apnea.Sleep202642821293PubTator, text miningPubMed
Structural insights into Sld3-Sld7-dependent Cdc45 loading during replication initiation.Nat Commun202642733061PubTator, text miningPubMed
Integrative Multi-omics Analysis for Prioritization of Candidate Genes in Polycystic Ovary Syndrome.FASEB J202642600058PubTator, text miningPubMed
The association between the MCM6 LCT-13910C>T variant and bone mineral density in patients with inflammatory bowel disease.Front Genet202642565205PubTator, text miningPubMed
Identification and Validation of an E2F Targets-Related Gene Signature Risk Score Predicting the Prognosis of Patients with Uveal Melanoma.Ocul Oncol Pathol202642553888PubTator, text miningPubMed
UBE2J2-mediated ubiquitination modification of MCM6 regulates proliferation and migration of cervical cancer cells.Am J Cancer Res202642465018PubTator, text miningPubMed
MCM8 variants in two patients with primary ovarian insufficiency: clinical findings and in vitro defective DNA repair revealed by an MCM8 double-mutant construct.Front Endocrinol (Lausanne)202642388858PubTator, text miningPubMed
Exploring epigenome-proteome interactions underlying post-surgical progression of non-functioning pituitary adenomas using hypernetwork modelling.J Transl Med202642337646PubTator, text miningPubMed
A 5mC-related gene signature predicts prognosis and therapy response in hepatocellular carcinoma.Sci Rep202642304060PubTator, text miningPubMed
Combining single cell and bulk transcriptomics with Mendelian randomization identifies gut microbiota related prognostic genes and mechanisms in thyroid cancer.Discov Oncol202642105187PubTator, text miningPubMed

1 to 10 of 2,153

See all 2,153 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4175

GET https://conductscience.org/api/genes/v1/4175/patents?page=2