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Gene · 4176

MCM7: minichromosome maintenance complex component 7

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MCM7: minichromosome maintenance complex component 7. Genes, record 4176. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4176

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Gene

Symbol
MCM7
HGNC
Name
minichromosome maintenance complex component 7
HGNC
NCBI Gene ID
4176
NCBI Gene
HGNC ID
HGNC:6950
HGNC
Ensembl
ENSG00000166508
NCBI Gene
Aliases
CDC47, MCM2, P1.1-MCM3, P1CDC47, P85MCM, PNAS146, PPP1R104
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P33993DNA replication licensing factor MCM771928Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1453627P33993Espacenet
EP 4650780 A22025-11-194491P33993Espacenet
EP 4641201 A22025-10-294035P33993Espacenet
EP 4641202 A22025-10-294819P33993Espacenet
WO 2025163163 A12025-08-076P33993Espacenet
JP 2025517969 A2025-06-124035P33993Espacenet
JP 2025517970 A2025-06-124491P33993Espacenet
KR 1020250017231 A2025-02-044819P33993Espacenet
US 11446398 B22022-09-2051702P33993Espacenet
JP 2022524081 A2022-04-27154673P33993Espacenet

1 to 10 of 47

See all 47 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,810

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMCM7 papersNewest fiscal year
P01CA022443Molecular Biology and Genetics of Human Tumor Viruses262025
P30CA016672Cancer Center Support Grant152025
P30CA008748Cancer Center Support Grant122025
P30CA016056Roswell Park Cancer Center Support Grant112025
P30CA014051Cancer Center Support (Core) Grant102025
P30CA014520UW Comprehensive Cancer Center Support92025
P30CA076292Moffitt Cancer Center Support Grant92025
R01GM045436Initiation of DNA Replication at Cell Origins in Yeast82025
P01CA013106Targeting Transcription and Splicing in Cancer62025
P30CA016086Cancer Center Support Grant62025

1 to 10 of 1,810Source NIH's project files

See all 1,810 nih grants

Papers3,001

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Taxonomy and phylogeny of the lichen genus Bunodophoron (Sphaerophoraceae, Lecanorales) in New Caledonia, with the description of two new species.MycoKeys202642763634PubTator, text miningPubMed
The USP46-MCM7-RAD51 axis confers oxaliplatin resistance in colon cancer by augmenting homologous recombination repair capacity.Acta Biochim Biophys Sin (Shanghai)202642517256PubTator, text miningPubMed
Corrigendum to "A TRIM28-MCM7 regulatory axis sustains DNA replication programs in glioblastoma" [Biochem. Biophys. Res. Commun. 829 (2026) 154150].Biochem Biophys Res Commun202642502028PubTator, text miningPubMed
Taxonomy and molecular evaluation of the Halosphaeriaceae (Microascales, Hypocreomycetidae).MycoKeys202642403426PubTator, text miningPubMed
Plexin A2 regulated the metastasis in breast cancer through MCM7.BMC Cancer202642399903PubTator, text miningPubMed
A TRIM28-MCM7 regulatory axis sustains DNA replication programs in glioblastoma.Biochem Biophys Res Commun202642308765PubTator, text miningPubMed
A Versatile Multiplexed Immunofluorescence Strategy for Efficient, Host-Independent, and Scalable Spatial Protein Profiling.Small Methods202642305051PubTator, text miningPubMed
Single-cell RNA sequencing reveals chemotherapy-induced apoptosis in acute myeloid leukemia via B cell depletion and M2 to M1 macrophage repolarization.Hum Genomics202642277943PubTator, text miningPubMed
Machine learning-driven multi-omics integration uncovers a senescence associated molecular axis in HCC.Front Immunol202642183188PubTator, text miningPubMed
Vitamin D3 and K2-loaded keratin nanoparticles inhibit breast cancer cell growth via MCM-7 downregulation and ROS induction.Int J Biol Macromol202642092663PubTator, text miningPubMed

1 to 10 of 3,001

See all 3,001 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4176

GET https://conductscience.org/api/genes/v1/4176/patents?page=2