Gene · 4232
MEST: mesoderm specific transcript
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MEST: mesoderm specific transcript. Genes, record 4232. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4232
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q5EB52 | Mesoderm-specific transcript homolog protein | 335 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents43
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 53275 | Q5EB52 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 591 | Q5EB52 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 19 | Q5EB52 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 8563 | Q5EB52 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7008 | Q5EB52 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7008 | Q5EB52 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 591 | Q5EB52 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 8563 | Q5EB52 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 19 | Q5EB52 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 8563 | Q5EB52 | Espacenet |
1 to 10 of 43
See all 43 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants787
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MEST papers | Newest fiscal year |
|---|---|---|---|
| P30ES025128 | Center for Human Health and the Environment (CHHE) | 14 | 2025 |
| P30DK072476 | Pennington/Louisiana NORC | 6 | 2025 |
| P30ES007048 | Environmental Exposures, Host Factors and Human Disease | 4 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 4 | 2025 |
| P30ES017885 | Michigan Center on Lifestage Environmental Exposures and Disease (M-LEEaD) | 4 | 2025 |
| P30ES023515 | Mount Sinai Center for Health and Environment Across the LifeSpan (HEALS) | 4 | 2025 |
| ZIACP010121 | Molecular Epidemiology Studies of Occupational and Environmental Exposures | 4 | 2025 |
| P30CA023108 | Cancer Center Support Grant | 3 | 2025 |
| P30DK056350 | Nutrition Obesity Research Center (NORC) | 3 | 2025 |
| P30ES009089 | Center for Environmental Health in Northern Manhattan | 3 | 2025 |
1 to 10 of 787Source NIH's project files
See all 787 nih grantsPapers1,361
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A Candidate MEST Splice-Site Variant in a Patient with Silver-Russell Syndrome-like Phenotype: First Report and Literature Review. | Genes (Basel) | 2026 | 42792886 | PubTator, text mining | PubMed |
| Genomic imprinting of the metabolic regulator gene Klf14 is regulated by a paternal sub-TAD anchored at Mest. | Genes Dev | 2026 | 42767818 | PubTator, text mining | PubMed |
| Pan-cancer screening and integrative multi-omics and deep learning reveal the prognostic significance of an IBD-CRC shared host-microbe signature in bladder urothelial carcinoma. | Transl Oncol | 2026 | 42715652 | PubTator, text mining | PubMed |
| Targeting MEST using cobicistat as a therapeutic strategy for gastric cancer through suppressing NF-κB signaling. | Front Oncol | 2026 | 42614207 | PubTator, text mining | PubMed |
| ANLN: A New Hub in Glutamine Metabolism of Lung Adenocarcinoma by scRNA-Seq and Machine Learning. | Oncol Res | 2026 | 42500572 | PubTator, text mining | PubMed |
| Deoxyribonucleic acid methylation abnormalities at imprinted loci in oligospermic and azoospermic men. | F S Sci | 2026 | 42242640 | PubTator, text mining | PubMed |
| Sperm Imprinted Gene Methylation and DNA Fragmentation in ICSI Outcomes: A Pilot Study. | Epigenomes | 2026 | 42201148 | PubTator, text mining | PubMed |
| Combined effects of urine exposure and cryopreservation on sperm quality: an in vitro study of retrograde ejaculation. | Asian J Androl | 2026 | 42169621 | PubTator, text mining | PubMed |
| Sinomenine attenuates the growth and immune evasion of gastric cancer by regulating the METTL3/MEST-mediated RhoA/ROCK2 signaling pathway. | Pathol Res Pract | 2026 | 42102486 | PubTator, text mining | PubMed |
| Investigation of multilocus imprinting disturbance (MLID) in 101 Beckwith-Wiedemann spectrum patients. | Clin Epigenetics | 2026 | 42036661 | PubTator, text mining | PubMed |
1 to 10 of 1,361
See all 1,361 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4232
GET https://conductscience.org/api/genes/v1/4232/patents?page=2