ConductScience.org, home

Gene · 4241

MELTF: melanotransferrin

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. MELTF: melanotransferrin. Genes, record 4241. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4241

On this page

Gene

Symbol
MELTF
HGNC
Name
melanotransferrin
HGNC
NCBI Gene ID
4241
NCBI Gene
HGNC ID
HGNC:7037
HGNC
Ensembl
ENSG00000163975
NCBI Gene
Aliases
CD228, FLJ38863, MAP97, MFI2, MGC4856, MTF1, MTf
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P08582Melanotransferrin7381Ensembl, GeneID, HGNC

Source UniProt

Patents86

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437629P08582Espacenet
EP 4650780 A22025-11-193710P08582Espacenet
EP 4641201 A22025-10-293297P08582Espacenet
JP 2025147176 A2025-10-068536P08582Espacenet
JP 2025532637 A2025-10-01108P08582Espacenet
JP 2025532652 A2025-10-01108P08582Espacenet
JP 2025529142 A2025-09-047005P08582Espacenet
WO 2025175123 A12025-08-21108P08582Espacenet
US 12371689 B22025-07-297005P08582Espacenet
JP 2025517969 A2025-06-123297P08582Espacenet

1 to 10 of 86

See all 86 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants793

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMELTF papersNewest fiscal year
P30ES006694Southwest Environmental Health Sciences Center122025
ZIABC010600AAA Proteins, Mechanisms of Their Functions and Related Diseases62025
P30CA008748Cancer Center Support Grant52025
ZIADK033008Mechanism of protein quality control at the endoplasmic reticulum52025
P30CA021765Cancer Center Support Grant (CCSG)42025
T32ES007091Training in Environmental Toxicology of Human Disease42025
P30CA010815Consolidated Basic Cancer Research Program32025
P30DK034854Integrated Epithelial and Muscosal Biology32025
R01CA163910Targeting ER stress response in B-cell chronic lymphocytic leukemia32025
R01GM127557Mechanisms regulating ER Proteostasis32025

1 to 10 of 793Source NIH's project files

See all 793 nih grants

Papers1,420

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification of melanotransferrin (MFI2) as a membrane target and an MFI2-directed aptamer as a theranostic tool for pancreatic ductal adenocarcinoma.Talanta202742727242PubTator, text miningPubMed
Nucleophagy as an emerging therapeutic vulnerability in cancer.Autophagy202642495958PubTator, text miningPubMed
Preclinical evaluation of 89Zr/177Lu/161Tb-labeled anti-CD228 monoclonal antibody for theranostics in skin cutaneous melanoma.Eur J Pharm Biopharm202642203156PubTator, text miningPubMed
Dual role of the OMM E3 Ub ligase MARCH5 in de novo peroxisome biogenesis and mitochondrial quality control through direct regulation of Pex26.bioRxiv202642182360PubTator, text miningPubMed
A CHK1-mediated phosphorylation switch suppresses human Topoisomerase 1-associated genomic instability.EMBO J202642129541PubTator, text miningPubMed
Corrigendum to 'Synthesis and structure-activity relationships of N - (3 - (1H-imidazol-2-yl) phenyl) - 3-phenylpropionamide derivatives as a novel class of covalent inhibitors of p97/VCP ATPase' [ Eur. J. Med. Chem. 248 (2023) 115094].
Eur J Med Chem202642106196PubTator, text miningPubMed
Lipid-anchored melanotransferrin mediates transferrin-independent iron uptake and ferritin storage in mammals.Cell Death Discov202641997899PubTator, text miningPubMed
Programmed cell death: a promising management for Alzheimer's disease.Apoptosis202641904723PubTator, text miningPubMed
Paradoxes in the Ontological Classification of Glia-Evidence for an Important New Class of Brain Cells with Primary Functions in Iron Regulation.Cells202641892302PubTator, text miningPubMed
The role of copper and cuproptosis in digestive system cancers: novel therapeutic strategies and mechanistic insights.Cancer Biol Ther202641837409PubTator, text miningPubMed

1 to 10 of 1,420

See all 1,420 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4241

GET https://conductscience.org/api/genes/v1/4241/patents?page=2