Gene · 4245
MGAT1: alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MGAT1: alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase. Genes, record 4245. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4245
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P26572 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 445 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents56
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 52559 | P26572 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 52560 | P26572 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 52561 | P26572 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 52562 | P26572 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 52563 | P26572 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 4792 | P26572 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2631 | P26572 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2631 | P26572 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4792 | P26572 | Espacenet |
| WO 2025093745 A1 | 2025-05-08 | 27 | P26572 | Espacenet |
1 to 10 of 56
See all 56 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,268
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MGAT1 papers | Newest fiscal year |
|---|---|---|---|
| R01CA206573 | Structure and function of Transient Receptor Potential Channels | 15 | 2025 |
| R01GM083144 | Characterization of mammalian COG complex-interacting Golgi trafficking machinery | 13 | 2025 |
| R01NS107253 | Single-Particle Cryo-EM Characterization of AMPA Receptor Functional States | 12 | 2025 |
| ZIAAI005022 | Antibody Neutralization Mechanisms | 12 | 2025 |
| R01HL103411 | Systems Biology of Glycosylation | 11 | 2025 |
| ZICAI005112 | Computational Tools for Structural Analysis | 11 | 2025 |
| ZIAAI005024 | Design Of Immunogens | 10 | 2025 |
| ZICAI005111 | Design of Antigenically-Specific Probes for Sera Analysis and MAb Isolation | 10 | 2025 |
| UM1AI144462 | Consortium for HIV/AIDS Vaccine Development | 9 | 2025 |
| P30GM124165 | NE-CAT: A Resource for Advanced Macromolecular Crystallography | 7 | 2025 |
1 to 10 of 1,268Source NIH's project files
See all 1,268 nih grantsPapers1,299
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Genetic and biochemical screens identify MGAT1 as a druggable glycosyltransferase target in STK11-mutant lung cancer. | J Biol Chem | 2026 | 42727848 | PubTator, text mining | PubMed |
| Mutations in the N-glycan branching enzyme MGAT1 promote invasiveness and EGF-stimulated proliferation and adhesion in neuroblastoma cells. | PLoS One | 2026 | 42721203 | PubTator, text mining | PubMed |
| Profiling neoadjuvant therapy response in rectal cancer using meta-analysis of publicly available transcriptomic RNA-seq datasets. | Mol Oncol | 2026 | 42703166 | PubTator, text mining | PubMed |
| Iterative Bump-and-Hole Engineering Creates a Bioorthogonal Reporter for N-Acetylglucosaminyltransferase I. | J Am Chem Soc | 2026 | 42378460 | PubTator, text mining | PubMed |
| mRNA delivery of a class 1/4 SARS-CoV-2 neutralizing antibody protects against diverse sarbecoviruses in a lethal mouse challenge model. | Proc Natl Acad Sci U S A | 2026 | 42258728 | PubTator, text mining | PubMed |
Statement of Retraction: MicroRNA miR-331-3p suppresses osteosarcoma progression via the Bcl-2/Bax and Wnt/β-Catenin signaling pathways and the epithelial-mesenchymal transition by targeting N-acetylglucosaminyltransferase I (MGAT1). | Bioengineered | 2026 | 42165821 | PubTator, text mining | PubMed |
| Deleterious effects of perfluorooctanesulfonate (PFOS) exposure on glucose and lipid metabolisms in the marine water flea Diaphanosoma celebensis. | Comp Biochem Physiol C Toxicol Pharmacol | 2026 | 41966289 | PubTator, text mining | PubMed |
| A preliminary study developing a scoring model incorporating fibrinogen-like protein 2 for predicting glucocorticoid resistance in thyroid eye disease. | Thyroid Res | 2026 | 41917995 | PubTator, text mining | PubMed |
| Exploring sex bias in cardiometabolic diseases. | Lipids Health Dis | 2026 | 41840637 | PubTator, text mining | PubMed |
| N-Glycoengineering of insect cells for tri-antennary N-glycan biosynthesis. | Sci Rep | 2026 | 41839924 | PubTator, text mining | PubMed |
1 to 10 of 1,299
See all 1,299 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4245
GET https://conductscience.org/api/genes/v1/4245/patents?page=2