Gene · 4256
MGP: matrix Gla protein
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MGP: matrix Gla protein. Genes, record 4256. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4256
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P08493 | Matrix Gla protein | 103 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents39
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 52736 | P08493 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 16409 | P08493 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 8696 | P08493 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 7029 | P08493 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 7029 | P08493 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 16409 | P08493 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 31572 | P08493 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 8696 | P08493 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 8696 | P08493 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 31572 | P08493 | Espacenet |
1 to 10 of 39
See all 39 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,562
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MGP papers | Newest fiscal year |
|---|---|---|---|
| R01HL081397 | Mechanism of Matrix Gla Protein (MGP); Adipose Fibrosis | 29 | 2025 |
| R01NS079353 | BMP and Notch crosstalk in cerebral arteriovenous malformations | 18 | 2025 |
| R01HL139675 | Switch of Osteogenesis in Vascular Calcification | 9 | 2025 |
| P30AG021332 | Wake Forest Claude D. Pepper OAIC - Renewal | 6 | 2025 |
| P30EY005722 | Center Core Grant for Vision Research | 6 | 2025 |
| T32AR007592 | Interdisciplinary Training Program in Muscle Biology | 6 | 2025 |
| P30DK017047 | Diabetes Research Center | 5 | 2025 |
| P30EY008098 | Core Grant for Vision Research | 5 | 2025 |
| P30EY010572 | Ophthalmology Core Facility | 5 | 2025 |
| R01HL158053 | Endothelial Regulation of Vascular Calcification | 5 | 2025 |
1 to 10 of 1,562Source NIH's project files
See all 1,562 nih grantsPapers3,332
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrated Multi-Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC. | Adv Sci (Weinh) | 2026 | 42801661 | PubTator, text mining | PubMed |
| Regulators of Mineralization and Long-Term Progression of Aortic Valve and Mitral Annular Calcification: MESA. | J Am Heart Assoc | 2026 | 42786596 | PubTator, text mining | PubMed |
| A Multifunctional Mesoporous Janus Separator With Optimized Mass Transport Regulation Enabling 800-Cycle Lithium-Oxygen Batteries. | Adv Sci (Weinh) | 2026 | 42733227 | PubTator, text mining | PubMed |
| Circulating matrix GLA protein during puberty in healthy and central precocious puberty children. | Endocr Connect | 2026 | 42696275 | PubTator, text mining | PubMed |
| Beyond Bone Health: Exploring the "Heart-Brain-Bone" Axis Modulated by Lipid-Soluble Nutrients (Omega-3, Vitamin D3, and Vitamin K2). | Nutrients | 2026 | 42654291 | PubTator, text mining | PubMed |
| Polyaspartic Acid-Doped With Robust Polymerized Hydrogel Armor Enhances Anti-Calcification of Decellularized Porcine Heart Valves. | Adv Healthc Mater | 2026 | 42638230 | PubTator, text mining | PubMed |
| Caspase-8 as a candidate mediator associated with everolimus resistance in neuroendocrine tumors. | J Mol Endocrinol | 2026 | 42615220 | PubTator, text mining | PubMed |
| Mitochondrial RNA modification in colorectal cancer: From single-cell analysis to machine learning-based risk modeling. | Comput Biol Chem | 2026 | 42600521 | PubTator, text mining | PubMed |
| Single-Cell atlas of aqueous humor outflow in glaucomatous Non-Human Primates identified MGP as a regulator of ECM remodeling. | Exp Eye Res | 2026 | 42562148 | PubTator, text mining | PubMed |
| From proteome-wide Mendelian randomization and multi-omics integration to functional validation: TGFB3 as a prioritized candidate in gastric adenocarcinoma. | Front Oncol | 2026 | 42518818 | PubTator, text mining | PubMed |
1 to 10 of 3,332
See all 3,332 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4256
GET https://conductscience.org/api/genes/v1/4256/patents?page=2