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ASAH1: N-acylsphingosine amidohydrolase 1
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Gene · 427

Papers1,873

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,873

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TitleJournalYearPMIDFound bySource
Metabolic targeting of ASAH1 in combination with carnosine as a therapeutic strategy for TNBC.Mol Metab202642815573PubTator, text miningPubMed
Lipid tail length dictates membrane disruption by carmofur analogs and reveals noncanonical modes of action.RSC Adv202642807973PubTator, text miningPubMed
Porphyromonas gingivalis-Derived Phosphoglycerol-isoC17:0-Dihydroceramide Reprograms Sphingolipid Metabolism in Human OECM-1 Oral Squamous Cell Carcinoma Cells.FASEB Bioadv202642781096PubTator, text miningPubMed
Sphingolipid metabolism contributes to sex dimorphism in COPD pathogenesis.JCI Insight202642771472PubTator, text miningPubMed
Dysregulation of Sphingolipid Metabolism in Non-Obstructive Azoospermia: Insights from Bioinformatics and a Busulfan-Induced Mouse Model.Reprod Sci202642722974PubTator, text miningPubMed
Fluorogenic Tissue-Based Assessment of Acid Ceramidase Activity.Bio Protoc202642656824PubTator, text miningPubMed
Therapeutic Effects of Ceranib-2 and Irinotecan Combination on Colon Cancer.Curr Issues Mol Biol202642651839PubTator, text miningPubMed
A 3D human retina model reveals a non-cell-autonomous and non-neuronal mechanism of photoreceptor loss in a lysosomal storage disorder.Sci Transl Med202642647598PubTator, text miningPubMed
ZMAT3 alleviates cell death in Fanconi anemia via adaptation of sphingolipid metabolism.Sci Adv202642536749PubTator, text miningPubMed
Keeping it acid ceramidase: How adiponectin protects in the glomerulus.J Pharmacol Exp Ther202642509125PubTator, text miningPubMed
Multiomic profiling of responses to clinical and novel bisphosphonates reveals extraskeletal effects on ageing related signatures.Signal Transduct Target Ther202642448670PubTator, text miningPubMed
Acid ceramidase modulates the lipid profile and exacerbates sensitivity to ferroptosis in WI-38 replicative senescent cells.Cell Death Dis202642431858PubTator, text miningPubMed
A human lysosomal storage disorder toolkit for decoding proteome landscapes in cortical-like and dopaminergic-like induced neurons.Proc Natl Acad Sci U S A202642384675PubTator, text miningPubMed
An LSEC-focused computational drug repurposing platform for liver fibrosis: Identification of vorinostat and other LSEC-protective candidates.bioRxiv202642244548PubTator, text miningPubMed
PSAP Protects Against Acute Myocardial Ischemia-Reperfusion Injury by Promoting ASAH1-Mediated Ceramide Metabolism.J Cardiovasc Transl Res202642234286PubTator, text miningPubMed
Death following high-dose AAV9 gene therapy in a patient with advanced SMA-PME.Mol Ther202642198847PubTator, text miningPubMed
xNNPCD identifies regulators of programmed cell death by integrating perturbation transcriptomes with cancer dependency profiles.bioRxiv202642182318PubTator, text miningPubMed
Farber Lipogranulomatosis With Spinal Muscular Atrophy With Progressive Myoclonic Epilepsy: Expanding the Phenotypic Spectrum.J Child Neurol202642175818PubTator, text miningPubMed
Acid ceramidase inhibition enhances BCL-2 targeting in venetoclax-resistant acute myeloid leukemia.Blood Neoplasia202641994327PubTator, text miningPubMed
Intersection of Spinal Muscular Atrophy and Progressive Myoclonic Epilepsy Syndrome: ASAH1 Gene.Ann Indian Acad Neurol202641964139PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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