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MITF: melanocyte inducing transcription factor

1 protein, 35 patents, 0 drugs, 0 trials, 3,844 NIH grants and 9,002 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMITFHGNC
Namemelanocyte inducing transcription factorHGNC
NCBI Gene ID4286NCBI Gene
HGNC IDHGNC:7105HGNC
EnsemblENSG00000187098NCBI Gene
AliasesCMM8, COMMAD, MI, MITF-A, WS2, WS2A, bHLHe32NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
O75030Microphthalmia-associated transcription factor52612Ensembl, GeneID, HGNCUniProt

Patents 35

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1912474O75030Espacenet
EP 4640849 A22025-10-292039O75030Espacenet
EP 4641201 A22025-10-2913685O75030Espacenet
JP 2025147176 A2025-10-0615294O75030Espacenet
JP 2025519096 A2025-06-242039O75030Espacenet
JP 2025517969 A2025-06-1213685O75030Espacenet
JP 2025517970 A2025-06-1212474O75030Espacenet
JP 2025028160 A2025-02-2815294O75030Espacenet
KR 1020250010750 A2025-01-2115294O75030Espacenet
EP 4487869 A22025-01-08345O75030Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3844

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant892,025NIH's project files
R01AR043369MITF from control of pigmentation to melanoma risk832,025NIH's project files
P01CA163222Targetable epigenetic and transcriptional mechanisms in melanoma thatshape the microenvironment662,025NIH's project files
P30CA016672Cancer Center Support Grant592,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program462,025NIH's project files
R01AR072304Therapeutic strategies for treatment of giant congenital melanocytic nevi172,025NIH's project files
ZIABC011028Clinical Studies of the Molecular Genetic Basis of Kidney Cancer172,025NIH's project files
ZIABC011038Molecular Therapeutics of Kidney Cancer: VHL Gene and Fumarate Hydratase Gene162,025NIH's project files
P30CA016520Abramson Cancer Center Support Grant142,025NIH's project files
P30CA086862Cancer Center Support Grant142,025NIH's project files

Papers 9002

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822710PubTator, text miningPubMed
42818319PubTator, text miningPubMed
42813601PubTator, text miningPubMed
42810595PubTator, text miningPubMed
42805312PubTator, text miningPubMed
42794453PubTator, text miningPubMed
42787358PubTator, text miningPubMed
42781952PubTator, text miningPubMed
42779635PubTator, text miningPubMed
42769533PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license