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Gene · 4287

ATXN3: ataxin 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ATXN3: ataxin 3. Genes, record 4287. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4287

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Gene

Symbol
ATXN3
HGNC
Name
ataxin 3
HGNC
NCBI Gene ID
4287
NCBI Gene
HGNC ID
HGNC:7106
HGNC
Ensembl
ENSG00000066427
NCBI Gene
Aliases
AT3, ATX3, JOS, MJD, MJD1, SCA3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P54252Ataxin-33617Ensembl, GeneID, HGNC

Source UniProt

Patents42

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4716542 A12026-04-0148P54252Espacenet
EP 4650780 A22025-11-1919543P54252Espacenet
JP 2025529142 A2025-09-04546P54252Espacenet
US 12371689 B22025-07-29546P54252Espacenet
JP 2025517970 A2025-06-1219543P54252Espacenet
JP 2025062604 A2025-04-146922P54252Espacenet
JP 2024123008 A2024-09-104923P54252Espacenet
JP 2023551068 A2023-12-0688P54252Espacenet
JP 2023549761 A2023-11-2988P54252Espacenet
JP 2023549167 A2023-11-2288P54252Espacenet

1 to 10 of 42

See all 42 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,882

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleATXN3 papersNewest fiscal year
R01NS086778MOLECULAR MECHANISMS OF NEUROPROTECTION IN POLYGLUTAMINE-DEPENDENT DEGENERATION142025
P41EB027061Technology to Realize the Full Potential of UHF MRI102025
P30ES009089Center for Environmental Health in Northern Manhattan72025
R01NS124854Targeting Cerebellar Endoplasmic Reticulum Calcium Handling in Essential Tremor72025
P01CA092584Structural Cell Biology of DNA Repair Machines62025
P40OD010440Caenorhabditis Genetics Center62025
T32CA009531Training Program in the Biology of Cancer62025
T32NS007222Training in Clinical and Basic Neuroscience52025
P30DK063491Diabetes Research Center (DRC)42025
P40OD018537Bloomington Drosophila Stock Center at Indiana University42025

1 to 10 of 1,882Source NIH's project files

See all 1,882 nih grants

Papers3,790

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Hereditary and Non-hereditary Cerebellar Ataxias in Latvia: Six Years of Experience at the National Reference Centre (ERN-RND Affiliated Partner).Cerebellum202642802208PubTator, text miningPubMed
Unified long-read panel for Parkinson's and repeat expansion disorders.NPJ Parkinsons Dis202642786195PubTator, text miningPubMed
MicroRNAs in polyglutamine diseases: Mechanistic insights, circulating biomarkers, and emerging microRNA-based therapeutic strategies.Neurobiol Dis202642716230PubTator, text miningPubMed
Convergent validity, responsiveness, and meaningful within-subject change of the PROM-Ataxia in spinocerebellar ataxias.J Neurol202642714627PubTator, text miningPubMed
Importin-8 silencing reduces Ataxin-3 aggregation and alleviates Machado-Joseph disease/spinocerebellar ataxia type 3.iScience202642699281PubTator, text miningPubMed
Predicting disease progression in progressive cerebellar ataxias: integrating clinical, imaging, fluid, genetic, and digital biomarkers.Front Neurol202642677125PubTator, text miningPubMed
Divergent somatic mutation patterns among human cerebellar neuron types.Neuron202642575091PubTator, text miningPubMed
Expanded ATXN10 Alleles in Neurodegenerative Disorders: A Case Series and Review of the Literature.Mov Disord Clin Pract202642569794PubTator, text miningPubMed
Expanded ATXN3 CAG Repeat is Stable in Human Purkinje Cells.Mov Disord202642568078PubTator, text miningPubMed
How Early Should I Refer My Patient? The Benefits of a Quick Ophthalmic Referral in Spinocerebellar Ataxias, a Case Series and Literature Review.Brain Sci202642512530PubTator, text miningPubMed

1 to 10 of 3,790

See all 3,790 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4287

GET https://conductscience.org/api/genes/v1/4287/patents?page=2