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MKI67: marker of proliferation Ki-67

1 protein, 55 patents, 0 drugs, 0 trials, 4,107 NIH grants and 6,766 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMKI67HGNC
Namemarker of proliferation Ki-67HGNC
NCBI Gene ID4288NCBI Gene
HGNC IDHGNC:7107HGNC
EnsemblENSG00000148773NCBI Gene
AliasesKIA, Ki-67, MIB-, MIB-1, PPP1R105NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P46013Proliferation marker protein Ki-673,2563Ensembl, GeneID, HGNCUniProt

Patents 55

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4694917 A12026-02-18622P46013Espacenet
EP 4650780 A22025-11-198486P46013Espacenet
EP 4641201 A22025-10-298658P46013Espacenet
EP 4641202 A22025-10-295436P46013Espacenet
JP 2025517969 A2025-06-128658P46013Espacenet
JP 2025517970 A2025-06-128486P46013Espacenet
KR 1020250017231 A2025-02-045436P46013Espacenet
US 12153054 B22024-11-261P46013Espacenet
JP 2024123008 A2024-09-104856P46013Espacenet
WO 2024161749 A2024-08-082P46013Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4107

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant422,025NIH's project files
P30CA016672Cancer Center Support Grant372,025NIH's project files
P30CA016056Roswell Park Cancer Center Support Grant302,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award252,025NIH's project files
P30CA016087Cancer Center Support Grant132,025NIH's project files
P50CA058223SPORE in Breast Cancer132,025NIH's project files
P30CA006973Regional Oncology Research Center112,025NIH's project files
P30CA068485Cancer Center Support Grant112,025NIH's project files
P30CA015704Cancer Center Support Grant102,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-2028102,025NIH's project files

Papers 6766

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42797373PubTator, text miningPubMed
42792719PubTator, text miningPubMed
42775805PubTator, text miningPubMed
42771562PubTator, text miningPubMed
42756106PubTator, text miningPubMed
42741635PubTator, text miningPubMed
42724469PubTator, text miningPubMed
42712484PubTator, text miningPubMed
42708797PubTator, text miningPubMed
42666328PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license