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Gene · 429

ASCL1: achaete-scute family bHLH transcription factor 1

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. ASCL1: achaete-scute family bHLH transcription factor 1. Genes, record 429. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/429

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
ASCL1
HGNC
Name
achaete-scute family bHLH transcription factor 1
HGNC
NCBI Gene ID
429
NCBI Gene
HGNC ID
HGNC:738
HGNC
Ensembl
ENSG00000139352
NCBI Gene
Aliases
ASH1, HASH1, MASH1, bHLHa46
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P50553Achaete-scute homolog 12360Ensembl, GeneID, HGNC

Source UniProt

Patents97

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4805378 A12026-09-16695P50553Espacenet
JP 2026076236 A2026-05-111P50553Espacenet
WO 2026048797 A2026-03-0532P50553Espacenet
JP 2026004568 A2026-01-1436018P50553Espacenet
JP 2025147176 A2025-10-061202P50553Espacenet
JP 2025147176 A2025-10-0614759P50553Espacenet
JP 2025529142 A2025-09-045536P50553Espacenet
KR 1020250128903 A2025-08-281P50553Espacenet
JP 2025122659 A2025-08-213P50553Espacenet
US 12371689 B22025-07-295536P50553Espacenet

1 to 10 of 97

See all 97 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants3,413

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA008748Cancer Center Support Grant752025
U24CA213274Coordinating center for the NCI small cell lung cancer research consortium432025
P30CA016672Cancer Center Support Grant322025
P50CA097186The Pacific Northwest Prostate Cancer SPORE212025
R35CA263816Novel therapeutic development for small cell lung cancer182025
P30CA015704Cancer Center Support Grant132025
R37CA241486Molecular mechanisms underlying lineage plasticity in prostate cancer132025
P01CA163227Androgen Receptor Action in Castration Resistant Prostate Cancer112025
R01EY021482Stimulation of Retinal Regeneration112025
P30CA006973Regional Oncology Research Center102025

1 to 10 of 3,413Source NIH's project files

See all 3,413 nih grants

Papers4,495

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42820295PubTator, text miningPubMed
42812792PubTator, text miningPubMed
42787995PubTator, text miningPubMed
42785991PubTator, text miningPubMed
42785309PubTator, text miningPubMed
42782345PubTator, text miningPubMed
42747234PubTator, text miningPubMed
42733321PubTator, text miningPubMed
42722432PubTator, text miningPubMed
42721975PubTator, text miningPubMed

1 to 10 of 4,495

See all 4,495 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/429

GET https://conductscience.org/api/genes/v1/429/patents?page=2