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MAP3K11: mitogen-activated protein kinase kinase kinase 11
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Gene · 4296

Papers1,505

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 1,505

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TitleJournalYearPMIDFound bySource
miR-4632-5p Alleviates Lumbar Disc Degeneration by Targeting MAP3K11: A Novel Role in Mitigating Nucleus Pulposus Cell Degeneration.Biochem Genet202642599634PubTator, text miningPubMed
Vav2 is a master regulator of repair against bacterial pore-forming toxins.Life Sci Alliance202642425763PubTator, text miningPubMed
MLK3 promotes atherosclerosis by regulating ferroptosis in macrophages.Inflamm Res202642323431PubTator, text miningPubMed
Multicytokine-based transcriptome-wide association study for 7 inflammatory skin disorders identifies candidate causal genes in keratinocytes.J Allergy Clin Immunol202642203178PubTator, text miningPubMed
Coordinated chromosome motion emerges from mechanical coupling mediated by the physical spindle environment.Mol Biol Cell202642054204PubTator, text miningPubMed
Mendelian Randomization Reveals Potential Drug Targets for Multiple Sclerosis Targeting Ferroptosis.CNS Neurol Disord Drug Targets202642002896PubTator, text miningPubMed
Protein Kinase D2 Regulates GRASP65 Phosphorylation and Golgi Ribbon Unlinking During G2/M Transition.Cells202641892354PubTator, text miningPubMed
Reactive oxygen species (ROS) in cancer: from mechanism to therapeutic implications.Signal Transduct Target Ther202641881983PubTator, text miningPubMed
Plasma metabolomic profiling reveals lipid biomarkers for early detection of exercise-induced myocardial ischemia.Medicine (Baltimore)202641861189PubTator, text miningPubMed
Decoding organ fibrosis: mechanistic insights and emerging therapeutic strategies.Signal Transduct Target Ther202641786685PubTator, text miningPubMed
Potential of SP1 as a prognostic marker and therapeutic target in acute myocardial infarction: a bioinformatics, Mendelian randomization and experimental validation study.Front Immunol202641782887PubTator, text miningPubMed
Pilot study: predicting the interplay between FOXO1 and its downstream long non-coding RNAs in HCC.Front Oncol202641777650PubTator, text miningPubMed
From Latent Manifolds to Targeted Molecular Probes: An Interpretable, Kinome-Scale Generative Machine Learning Framework for Family-Based Kinase Ligand Design.Biomolecules202641750280PubTator, text miningPubMed
Cancer neuroscience: signaling pathways and new therapeutic strategies for cancer.Signal Transduct Target Ther202641724757PubTator, text miningPubMed
MicroRNAs as biomarkers and therapeutic targets in pterygia: A systematic review with quantitative synthesis.Surv Ophthalmol202641643858PubTator, text miningPubMed
Regulation of E-cadherin by mixed lineage kinase 3 (MLK3) mediates cell adhesion in ovarian cancer spheroids.Biochim Biophys Acta Mol Cell Res202641513046PubTator, text miningPubMed
Leveraging protein language models to identify complex trait associations with previously inaccessible classes of functional rare variants.Cell Genom202641265447PubTator, text miningPubMed
Systematic druggable genome-wide Mendelian randomization identifies therapeutic targets for gout.Naunyn Schmiedebergs Arch Pharmacol202641212276PubTator, text miningPubMed
Depletion of LINC01133 from cancer-associated fibroblasts exacerbates the progression of gastric adenocarcinoma.iScience202541321626PubTator, text miningPubMed
Protopanaxadiol induces apoptosis through JNK signaling pathway and targeting MLK3 in human melanoma.J Ginseng Res202541268315PubTator, text miningPubMed

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Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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