Gene · 432
ASGR1: asialoglycoprotein receptor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ASGR1: asialoglycoprotein receptor 1. Genes, record 432. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/432
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P07306 | Asialoglycoprotein receptor 1 | 291 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents95
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4727595 A2 | 2026-04-22 | 29 | P07306 | Espacenet |
| EP 4705462 A2 | 2026-03-11 | 80 | P07306 | Espacenet |
| JP 2026016543 A | 2026-02-03 | 1 | P07306 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 37938 | P07306 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2701 | P07306 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 332 | P07306 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2289 | P07306 | Espacenet |
| JP 2025535145 A | 2025-10-22 | 1 | P07306 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 332 | P07306 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2289 | P07306 | Espacenet |
1 to 10 of 95
See all 95 patentsDrugs2
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
Trials6
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT04516291 | VUPANORSEN | PHASE2 | 2022-10-04 | ClinicalTrials.gov |
| NCT04459767 | VUPANORSEN | PHASE1 | ClinicalTrials.gov | |
| NCT03514420 | VUPANORSEN | PHASE2 | 2021-02-16 | ClinicalTrials.gov |
| NCT03455777 | VUPANORSEN | PHASE2 | ClinicalTrials.gov | |
| NCT03371355 | VUPANORSEN | PHASE2 | 2021-02-01 | ClinicalTrials.gov |
| NCT03360747 | VUPANORSEN | PHASE2 | 2021-01-07 | ClinicalTrials.gov |
NIH grants1,038
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ASGR1 papers | Newest fiscal year |
|---|---|---|---|
| R01HL089224 | Carbohydrate-Mediated Platelet Clearance | 8 | 2025 |
| R01DK078244 | Molecular Basis of Pathogenicity of IgA1-containing Immune Complexes | 7 | 2025 |
| P30DK078392 | Digestive Health Center (DHC): Bench to Bedside Research in Pediatric Digestive Disease | 5 | 2025 |
| P30DK084567 | Mayo Center for Cell Signaling in Gastroenterology | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA013330 | Cancer Center Support Grant | 4 | 2025 |
| P30CA045508 | CSHL Cancer Center Support Grant | 4 | 2025 |
| P30CA093373 | Cancer Center Support Grant P30 | 4 | 2025 |
| R01CA255727 | Extracellular Vesicle-Based Digital Scoring Assay for Detecting Early-stage Hepatocellular Carcinoma | 4 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 3 | 2025 |
1 to 10 of 1,038Source NIH's project files
See all 1,038 nih grantsPapers2,727
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A hepatic-targeting NIR fluorescent probe simultaneously unlocked by BChE and high viscosity in diabetes mellitus. | Spectrochim Acta A Mol Biomol Spectrosc | 2027 | 42785018 | PubTator, text mining | PubMed |
| Genetically engineered porcine liver: a new era in transplantation. | Int J Surg | 2026 | 42808109 | PubTator, text mining | PubMed |
| Re: ASGR1 Deficiency Promotes Liver Fibrosis by Enhancing Pro-Inflammatory Arachidonic Acid Metabolism and ALP Secretion. | Immun Inflamm Dis | 2026 | 42806895 | PubTator, text mining | PubMed |
| Targeted dual degradation of GPC-3 and VEGFR with multivalent DNA nanoflower-based LYTACs for hepatocellular carcinoma therapy. | J Control Release | 2026 | 42777829 | PubTator, text mining | PubMed |
| Hyperbaric Oxygen Treatment Enhances Definitive Endoderm Differentiation and Hepatic Maturation of Human-Induced Pluripotent Stem Cells in Association with mTORC2-Dependent AKT Phosphorylation. | Int J Stem Cells | 2026 | 42750199 | PubTator, text mining | PubMed |
| Ligand Arm Length Governs Geometry, Spin State, and Reactivity in Unsymmetrical β-Diketiminato Nickel(II) and Nickel(I) Complexes. | Inorg Chem | 2026 | 42734380 | PubTator, text mining | PubMed |
| Advances in galactose-based small-molecule hepatocyte-targeting probes for detecting biomarkers in hepatocellular carcinoma. | Front Chem | 2026 | 42694819 | PubTator, text mining | PubMed |
| A ternary nanocomplex for hepatocyte-targeted gene delivery and treatment of metabolic dysfunction-associated steatotic liver disease. | RSC Adv | 2026 | 42626613 | PubTator, text mining | PubMed |
| DNA methylation informs adult cardiovascular risk and prevention for low birthweight individuals. | J Glob Health | 2026 | 42596884 | PubTator, text mining | PubMed |
| Decoding the Complexity of Hepatocellular Carcinoma: Clinical Challenges and Targeting HuR as a Novel Therapeutic Strategy. | Livers | 2026 | 42583674 | PubTator, text mining | PubMed |
1 to 10 of 2,727
See all 2,727 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/432
GET https://conductscience.org/api/genes/v1/432/patents?page=2