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Gene · 4320

MMP11: matrix metallopeptidase 11

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MMP11: matrix metallopeptidase 11. Genes, record 4320. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4320

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Gene

Symbol
MMP11
HGNC
Name
matrix metallopeptidase 11
HGNC
NCBI Gene ID
4320
NCBI Gene
HGNC ID
HGNC:7157
HGNC
Ensembl
ENSG00000099953
NCBI Gene
Aliases
SL-3, ST3, STMY3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P24347Stromelysin-34880Ensembl, GeneID, HGNC

Source UniProt

Patents45

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4824266 A12026-10-2174P24347Espacenet
EP 4773979 A12026-07-15194P24347Espacenet
EP 4650780 A22025-11-19275P24347Espacenet
JP 2025147176 A2025-10-068765P24347Espacenet
JP 2025529142 A2025-09-047043P24347Espacenet
US 12371689 B22025-07-297043P24347Espacenet
JP 2025517970 A2025-06-12275P24347Espacenet
JP 2025512333 A2025-04-17822P24347Espacenet
JP 2025028160 A2025-02-288765P24347Espacenet
KR 1020250010750 A2025-01-218765P24347Espacenet

1 to 10 of 45

See all 45 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,360

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMMP11 papersNewest fiscal year
P30CA016672Cancer Center Support Grant92025
ZIAHD001901Molecular mechanism of thyroid hormone receptor function during metamorphosis72025
P30CA006927Comprehensive Cancer Center Program at Fox Chase52025
P30CA013330Cancer Center Support Grant52025
P50CA116201Mayo Clinic Breast Cancer SPORE52025
P30CA008748Cancer Center Support Grant42025
P30CA068485Cancer Center Support Grant42025
U54CA1186381/3 Morehouse School of Medicine/Tuskegee University/University of Alabama at Birmingham O'Neal Comprehensive Cancer Center Partnership42025
P30CA006973Regional Oncology Research Center32025
P30CA016087Cancer Center Support Grant32025

1 to 10 of 1,360Source NIH's project files

See all 1,360 nih grants

Papers3,235

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Single-cell RNA sequencing in diabetic foot ulcers: pathogenesis, biomarkers, and translational potential.Front Clin Diabetes Healthc202642757034PubTator, text miningPubMed
A Composite Histopathologic Invasion Score Predicts Lymph Node Metastasis in Gastric Cancer.J Clin Med202642739515PubTator, text miningPubMed
Single-cell transcriptomics deciphers cancer-associated fibroblast heterogeneity and immune regulatory mechanisms in the bladder cancer tumor microenvironment.Front Cell Dev Biol202642729537PubTator, text miningPubMed
Clinical Significance of Tumor Invasion Gene Profiling in Early-Stage Hormone Receptor-Positive Breast Cancer: A Cross-Sectional Study.Health Sci Rep202642416217PubTator, text miningPubMed
Distinct Molecular Signature of Earlobe Keloids: Integrated Transcriptomic Analysis of Extracellualr Matrix, Metalloproteinase, and Metabolic Pathways.Aesthetic Plast Surg202642414644PubTator, text miningPubMed
Dissection of the EIAV Core Packaging Region Identifies SL2 Stem and SL2-SL3 Junction as Gag-Associated Packaging Determinants and Antiviral Targets.Int J Mol Sci202642278261PubTator, text miningPubMed
Targeting VEGF signaling and stromal remodeling enhances chemoimmunotherapy efficacy in esophageal cancer.J Immunother Cancer202642173653PubTator, text miningPubMed
Remdesivir and Favipiravir as potential antivirals for poliovirus: In vitro efficacy and RNA-dependent RNA polymerase binding analysis.Virology202642150251PubTator, text miningPubMed
Distribution and molecular drivers of the 21-gene recurrence score in early breast cancer with low, intermediate, and high estrogen receptor expression.Front Immunol202642148109PubTator, text miningPubMed
TAPINTO: A Novel Algorithm for Tumor-Associated Antigen Prediction Based on Information about Target Overexpression.Comput Struct Biotechnol J202642146903PubTator, text miningPubMed

1 to 10 of 3,235

See all 3,235 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4320

GET https://conductscience.org/api/genes/v1/4320/patents?page=2