Gene · 434
ASIP: agouti signaling protein
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ASIP: agouti signaling protein. Genes, record 434. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/434
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P42127 | Agouti-signaling protein | 132 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents41
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 36943 | P42127 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9552 | P42127 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 1203 | P42127 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 1204 | P42127 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 5537 | P42127 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 5537 | P42127 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 9552 | P42127 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3643 | P42127 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 3644 | P42127 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 1203 | P42127 | Espacenet |
1 to 10 of 41
See all 41 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants433
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ASIP papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 7 | 2025 |
| P30CA177558 | University of Kentucky Markey Cancer Center – Cancer Center Support Grant | 6 | 2025 |
| P30ES010126 | UNC Center for Environmental Health and Susceptibility | 6 | 2025 |
| T32CA165990 | Interdisciplinary Research Training in Cancer Biology | 6 | 2025 |
| P01CA163222 | Targetable epigenetic and transcriptional mechanisms in melanoma thatshape the microenvironment | 4 | 2025 |
| R01CA241623 | The Role of Genetic Risk Factors in Keratinocyte Carcinoma Susceptibility | 4 | 2025 |
| ZIACP004410 | Family Studies | 4 | 2025 |
| K24AR069760 | Patient oriented research and mentoring program in dermatologic diseases | 3 | 2025 |
| P30CA014089 | University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG) | 3 | 2025 |
1 to 10 of 433Source NIH's project files
See all 433 nih grantsPapers654
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Molecular and Evolutionary Basis of Avian Plumage Colour. | Biology (Basel) | 2026 | 42510724 | PubTator, text mining | PubMed |
| ASIP Variants in Livestock: It's Not Black and White. | Anim Genet | 2026 | 42237701 | PubTator, text mining | PubMed |
| Agouti signalling protein and triglyceride-glucose index in early pregnancy with gestational diabetes: a prospective cohort study. | J Obstet Gynaecol | 2026 | 42101196 | PubTator, text mining | PubMed |
| The ASIP Cys-98 Allele Is Not Associated With Black Coat Color in Water Buffaloes. | Anim Genet | 2026 | 41964159 | PubTator, text mining | PubMed |
| Structural Coloration and Carotenoids Together Create the Vibrant Colors of Peafowl Feathers. | Animals (Basel) | 2026 | 41897879 | PubTator, text mining | PubMed |
| Neurogenesis and the Epigenetic Landscape: Role of Histone Modifications and Chromatin Remodeling. | Brain Behav | 2026 | 41601423 | PubTator, text mining | PubMed |
| Blocking ASIP to Protect MC1R Signaling and Mitigate Melanoma Risk: An In Silico Study. | Pharmaceuticals (Basel) | 2026 | 41599712 | PubTator, text mining | PubMed |
| Molecular effects of transposable element sequences in mammalian cells. | Genome Biol | 2025 | 41299541 | PubTator, text mining | PubMed |
| Genetic imputation of transcriptome and proteome illuminates novel therapeutic targets of cutaneous melanoma. | Brief Bioinform | 2025 | 41148223 | PubTator, text mining | PubMed |
| A mosaic of modular variation at a single gene underpins convergent plumage coloration. | Science | 2025 | 41100596 | PubTator, text mining | PubMed |
1 to 10 of 654
See all 654 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/434
GET https://conductscience.org/api/genes/v1/434/patents?page=2