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MPO: myeloperoxidase

1 protein, 129 patents, 1 drug, 7 trials, 10,330 NIH grants and 39,473 papers.

Gene 6

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMPOHGNC
NamemyeloperoxidaseHGNC
NCBI Gene ID4353NCBI Gene
HGNC IDHGNC:7218HGNC
EnsemblENSG00000005381NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P05164Myeloperoxidase74549Ensembl, GeneID, HGNCUniProt

Patents 129

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
US 12560619 B22026-02-2485P05164Espacenet
JP 2026501772 A2026-01-164P05164Espacenet
JP 2026004568 A2026-01-1454486P05164Espacenet
JP 2025541179 A2025-12-1826P05164Espacenet
JP 2025538321 A2025-11-281P05164Espacenet
EP 4641201 A22025-10-29436P05164Espacenet
EP 4641202 A22025-10-294352P05164Espacenet
EP 4630459 A12025-10-1526P05164Espacenet
JP 2025147176 A2025-10-068840P05164Espacenet
JP 2025529142 A2025-09-047063P05164Espacenet

Drugs 1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
VERDIPERSTATCHEMBL4297594Myeloperoxidase inhibitorINHIBITORChEMBL

Trials 7

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT05086094VERDIPERSTATClinicalTrials.gov
NCT04616456VERDIPERSTATEARLY_PHASE1ClinicalTrials.gov
NCT04436510VERDIPERSTATPHASE2/PHASE32023-06-12ClinicalTrials.gov
NCT04297683VERDIPERSTATPHASE2/PHASE3ClinicalTrials.gov
NCT03952806VERDIPERSTATPHASE32023-09-29ClinicalTrials.gov
NCT02388295VERDIPERSTATPHASE22017-09-25ClinicalTrials.gov
NCT01527695VERDIPERSTATPHASE2ClinicalTrials.gov

NIH grants 10330

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant792,025NIH's project files
P30CA008748Cancer Center Support Grant512,025NIH's project files
ZIAAR041199Systemic Autoimmunity492,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)322,025NIH's project files
P30ES005605Environmental Health Sciences Research Center242,025NIH's project files
P42ES004705Toxic substances in the environment232,025NIH's project files
ZIDAR041180Clinical Support Services for the NIAMS Intramural Research Program232,025NIH's project files
P30DK017047Diabetes Research Center212,025NIH's project files
P30ES010126UNC Center for Environmental Health and Susceptibility202,025NIH's project files
P01HL116263HDL Function in Human Disease192,025NIH's project files

Papers 39473

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42825327PubTator, text miningPubMed
42824523PubTator, text miningPubMed
42824020PubTator, text miningPubMed
42822388PubTator, text miningPubMed
42821128PubTator, text miningPubMed
42819188PubTator, text miningPubMed
42816391PubTator, text miningPubMed
42815966PubTator, text miningPubMed
42811949PubTator, text miningPubMed
42810472PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license