Gene · 4359
MPZ: myelin protein zero
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MPZ: myelin protein zero. Genes, record 4359. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4359
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P25189 | Myelin protein P0 | 248 | 2 | Ensembl, GeneID, HGNC |
Source UniProt
Patents33
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 54387 | P25189 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 54388 | P25189 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 15430 | P25189 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 75378 | P25189 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2686 | P25189 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2686 | P25189 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 15430 | P25189 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 75378 | P25189 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 31779 | P25189 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 31780 | P25189 | Espacenet |
1 to 10 of 33
See all 33 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants694
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MPZ papers | Newest fiscal year |
|---|---|---|---|
| T32GM007526 | Medical Genetics Research Fellowship Program | 4 | 2025 |
| ZIANS003129 | Molecular and Clinical Manifestations of Matrix and Aggregate Myopathies | 4 | 2025 |
| R01DC017461 | Engineering multi-lineage inner ear organoids | 3 | 2025 |
| R01NS028840 | Mitogenic Activities in Neurofibromatosis | 3 | 2025 |
| R01NS072248 | Genome Studies in Hereditary Spastic Paraplegia- Beyond the Exome | 3 | 2025 |
| U24DC013983 | NIDCD National Temporal Bone Hearing and Balance Pathology Resource Registry | 3 | 2025 |
| P30CA062203 | Cancer Center Support Grant | 2 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 2 | 2025 |
| P30EY025580 | Multidisciplinary Investigations in Visual Science | 2 | 2025 |
| R01EY024605 | Choriocapillaris Protection and Replacement in AMD | 2 | 2025 |
1 to 10 of 694Source NIH's project files
See all 694 nih grantsPapers1,500
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Late-onset CMT neuropathy in the NGS era: a 10-year retrospective study. | J Neurol | 2026 | 42799779 | PubTator, text mining | PubMed |
| A Reproducible Transcriptomic Program of Neurofibroma-to-Malignant Peripheral Nerve Sheath Tumor Transformation. | Genes Chromosomes Cancer | 2026 | 42765715 | PubTator, text mining | PubMed |
| Bioactive keratin-pectin methacrylate multifilament nerve conduits for functional regeneration across segmental nerve defects. | Int J Biol Macromol | 2026 | 42748994 | PubTator, text mining | PubMed |
| A Case Report of a Novel Myelin Protein Zero (MPZ) Pathogenic Variant in Charcot-Marie-Tooth Disease Combined With Type 2 Diabetes. | Case Rep Genet | 2026 | 42732363 | PubTator, text mining | PubMed |
| Unveiling novel transcriptomic prognostic biomarkers for specific breast cancer subtypes and treatment regimens. | Pharmacol Rep | 2026 | 42714781 | PubTator, text mining | PubMed |
| [Clinical pattern and evolution of Charcot-Marie-Tooth disease in pediatrics]. | Medicina (B Aires) | 2026 | 42659543 | PubTator, text mining | PubMed |
| Hereditary Polyneuropathy Experience of a Tertiary Single-Center in Türkiye: Beyond the Tip of the Iceberg. | Clin Genet | 2026 | 42552261 | PubTator, text mining | PubMed |
| Case Report: Schwann cell reprogramming and PDGF-driven nerve hypertrophy in an NF1 patient with CIDP-like autoimmunity. | Front Immunol | 2026 | 42539570 | PubTator, text mining | PubMed |
| High-Resolution Ultrasound Evaluation of Nerves and Muscles at Multiple Sites in Charcot-Marie-Tooth Disease. | J Ultrasound Med | 2026 | 42435318 | PubTator, text mining | PubMed |
| Functional disease progression in children with inherited peripheral neuropathies: A prospective cohort study. | J Neuromuscul Dis | 2026 | 42396985 | PubTator, text mining | PubMed |
1 to 10 of 1,500
See all 1,500 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4359
GET https://conductscience.org/api/genes/v1/4359/patents?page=2