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Gene · 4487

MSX1: msh homeobox 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MSX1: msh homeobox 1. Genes, record 4487. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4487

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Gene

Symbol
MSX1
HGNC
Name
msh homeobox 1
HGNC
NCBI Gene ID
4487
NCBI Gene
HGNC ID
HGNC:7391
HGNC
Ensembl
ENSG00000163132
NCBI Gene
Aliases
ECTD3, HOX7, HYD1, OFC5, STHAG1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P28360Homeobox protein MSX-13030Ensembl, GeneID, HGNC

Source UniProt

Patents34

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1454113P28360Espacenet
EP 4650780 A22025-11-1910578P28360Espacenet
JP 2025147176 A2025-10-0615310P28360Espacenet
JP 2025147176 A2025-10-0616615P28360Espacenet
JP 2025517970 A2025-06-1210578P28360Espacenet
JP 2025028160 A2025-02-2815310P28360Espacenet
JP 2025028160 A2025-02-2816615P28360Espacenet
KR 1020250010750 A2025-01-2115310P28360Espacenet
KR 1020250010750 A2025-01-2116615P28360Espacenet
JP 2024109657 A2024-08-1415149P28360Espacenet

1 to 10 of 34

See all 34 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,445

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMSX1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant72025
U54GM104942West Virginia Clinical and Translational Science Institute: A Statewide Organization Building Research Excellence and Engaging Communities to Improve Health72025
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant52025
P30ES005605Environmental Health Sciences Research Center52025
R01DE017914Molecular Interactions during Neural Crest Formation52025
R01HD068524Molecular signaling in uterine receptivity to implantation52025
R01LM012806Predicting Phenotype by Deep Learning Heterogeneous Multi-Omics Data52025
P30CA016672Cancer Center Support Grant42025
T90DE023520University of Iowa Institutional Training Program in Oral Health Research42025
P30CA016042Cancer Center Support Grant32025

1 to 10 of 1,445Source NIH's project files

See all 1,445 nih grants

Papers2,388

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Niche-Mediated Neural Priming Enables Robust and Scalable Generation of Human Choroid Plexus Organoids.Adv Sci (Weinh)202642675788PubTator, text miningPubMed
Ependymomas are cancers of the pre-neural crest/roof plate lineage.bioRxiv202642523223PubTator, text miningPubMed
Exploring DNA methylation profiles in the pathogenesis of human osteoporosis via whole-genome bisulfite sequencing.PLoS One202642461885PubTator, text miningPubMed
A Combination of Variants in SEPTIN9 and MSX1 Genes Leads to the Formation of Orofacial Clefts.Genes Cells202642429105PubTator, text miningPubMed
Integrative multi-omics analysis identifies a mitochondrial dysfunction-associated diagnostic signature, molecular subtypes, and drug repurposing candidates for keloid disease.Burns202642413388PubTator, text miningPubMed
Identification of tumor-promoting functions of the Homeobox family transcription factor MSX1 in cervical cancer.Cell Death Discov202642248834PubTator, text miningPubMed
A Signaling-Threshold Framework for Human Tooth Agenesis: Integrating Molecular Genetics with Developmental Field Theory.Int J Mol Sci202642196506PubTator, text miningPubMed
Integrated Genetic Networks and Epigenetic Regulation inTooth Development and Maturation.Cells202641972710PubTator, text miningPubMed
MSX1 variant causes nonsyndromic tooth agenesis in a Japanese patient.Hum Genome Var202641927542PubTator, text miningPubMed
Genetic Aspects of Dental Impaction: A Scoping Review.Genes (Basel)202641898799PubTator, text miningPubMed

1 to 10 of 2,388

See all 2,388 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4487

GET https://conductscience.org/api/genes/v1/4487/patents?page=2