Gene · 4488
MSX2: msh homeobox 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MSX2: msh homeobox 2. Genes, record 4488. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4488
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P35548 | Homeobox protein MSX-2 | 267 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents39
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 54114 | P35548 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 990 | P35548 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15311 | P35548 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 990 | P35548 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 31812 | P35548 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15311 | P35548 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15311 | P35548 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 31812 | P35548 | Espacenet |
| JP 2024109657 A | 2024-08-14 | 15150 | P35548 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 31812 | P35548 | Espacenet |
1 to 10 of 39
See all 39 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,792
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MSX2 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| R01CA067007 | Mismatch Repair and Carcinogenesis | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 5 | 2025 |
| K12HD001271 | Colorado Women's Reproductive Health Research Career Development Center | 4 | 2025 |
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 4 | 2025 |
| P30ES007033 | University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment | 4 | 2025 |
| R01HD068524 | Molecular signaling in uterine receptivity to implantation | 4 | 2025 |
| R35GM119465 | Unraveling mechanisms of genome regulation to understand and improvehuman health | 4 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,792Source NIH's project files
See all 1,792 nih grantsPapers2,792
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Two Unrelated Families With Noncoding Duplications Upstream of MSX2 Refine the Critical Regulatory Region Likely Involved in Cranial Bone Development and a Cleidocranial Dysplasia-Like Phenotype. | Hum Mutat | 2026 | 42609732 | PubTator, text mining | PubMed |
| Leveraging the genetics of human face shape boosts the discovery of orofacial cleft risk loci. | HGG Adv | 2026 | 42482381 | PubTator, text mining | PubMed |
| Breast cancer risk genes affecting individual radiosensitivity. | Sci Rep | 2026 | 42289459 | PubTator, text mining | PubMed |
| Type E endothelial cells orchestrate embryonic skeletogenesis via chondrogenic priming of skeletal progenitors. | J Orthop Translat | 2026 | 42182072 | PubTator, text mining | PubMed |
| Uncovering the role of the PPR protein PHOTOSYSTEM ONE BIOGENESIS FACTOR6 in splicing chloroplast group II introns. | J Integr Plant Biol | 2026 | 42135903 | PubTator, text mining | PubMed |
| Evidence-based classification of genes implicated in craniosynostosis disorders using the ClinGen curation framework. | Genet Med | 2026 | 42059179 | PubTator, text mining | PubMed |
| Raman spectroscopy enables highly sensitive profiling of osteogenic mineralization in periodontal organoids. | Arch Oral Biol | 2026 | 42019144 | PubTator, text mining | PubMed |
| BMP4 signaling regulates the expression of signals and transcription factors for coordinated cytodifferentiation in the murine ureter. | Biochem J | 2026 | 42017529 | PubTator, text mining | PubMed |
| Neurobiology of language in autism: a systematic review of pediatric studies. | Brain Imaging Behav | 2026 | 41880035 | PubTator, text mining | PubMed |
| Molecular Origin of Correlated Bath Effects in Photoinduced Charge Transfer Dynamics in Polar Solvents. | J Phys Chem Lett | 2026 | 41838668 | PubTator, text mining | PubMed |
1 to 10 of 2,792
See all 2,792 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4488
GET https://conductscience.org/api/genes/v1/4488/patents?page=2