Gene · 4508
MT-ATP6: mitochondrially encoded ATP synthase membrane subunit 6
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MT-ATP6: mitochondrially encoded ATP synthase membrane subunit 6. Genes, record 4508. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4508
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P00846 | ATP synthase F(0) complex subunit a | 226 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents16
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026515744 A | 2026-05-19 | 323 | P00846 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2724 | P00846 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2724 | P00846 | Espacenet |
| WO 2024214081 A1 | 2024-10-17 | 323 | P00846 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 52325 | P00846 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 155296 | P00846 | Espacenet |
| JP 2022511502 A | 2022-01-31 | 58 | P00846 | Espacenet |
| KR 1020210100656 A | 2021-08-17 | 30 | P00846 | Espacenet |
| WO 2020117952 A2 | 2020-06-11 | 30 | P00846 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 269 | P00846 | Espacenet |
1 to 10 of 16
See all 16 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,315
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MT-ATP6 papers | Newest fiscal year |
|---|---|---|---|
| R35GM118141 | Mitochondrial Biogenesis in Health and Disease | 7 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30AG028740 | University of Florida Older Americans Independence Center (OAIC) | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| RM1HG008935 | Center for dynamic RNA epitranscriptomes - Renewal | 4 | 2025 |
| P20GM103434 | West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE) | 3 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 3 | 2025 |
| P30CA014195 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 3 | 2025 |
| P50CA097186 | The Pacific Northwest Prostate Cancer SPORE | 3 | 2025 |
1 to 10 of 1,315Source NIH's project files
See all 1,315 nih grantsPapers3,065
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Mitochondrial DNA methylation as a bridge: Linking indoor air purification to alleviated cardiovascular impairments in young adults. | Environ Res | 2026 | 42785507 | PubTator, text mining | PubMed |
| Co-mutation Based Genetic Networks to Infer Temporal Mutation Dynamics in Ancient Human Mitochondrial Genomes. | J Mol Evol | 2026 | 42730943 | PubTator, text mining | PubMed |
| Distinct Urea Cycle Dysfunction Profiles Differentiate Acute Metabolic Decompensation in TMEM70 and MT-ATP6-Related Mitochondrial ATP Synthase Defects. | J Inherit Metab Dis | 2026 | 42722418 | PubTator, text mining | PubMed |
| De Novo Assembly and Comparative Analysis of the Complete Mitochondrial Genome of Mesenchytraeus (Annelida, Enchytraeidae). | Ecol Evol | 2026 | 42699409 | PubTator, text mining | PubMed |
| Interim analysis of an international multi-site prospective natural history study evaluating the clinical presentation and progression of Leigh syndrome spectrum disorders. | Ther Adv Rare Dis | 2026 | 42662191 | PubTator, text mining | PubMed |
| Advances in Primary Mitochondrial Diseases: Diagnosis, Natural History Studies and Clinical Trials. | Genes (Basel) | 2026 | 42650043 | PubTator, text mining | PubMed |
| The complete mitochondrial genome of the thrips predator Montandoniola moraguesi (Hemiptera: Anthocoridae) and its phylogenetic analysis. | Mitochondrial DNA B Resour | 2026 | 42591940 | PubTator, text mining | PubMed |
| Complete Mitochondrial Genome of Turrum coeruleopinnatum Provides Phylogenetic Context and Candidate Selection Signals Within Carangidae. | Biochem Genet | 2026 | 42560611 | PubTator, text mining | PubMed |
| Integrative taxonomy reveals two new species of Itajahya Möller (Phallaceae, Phallales) in Brazil. | PLoS One | 2026 | 42555600 | PubTator, text mining | PubMed |
| Toxicity Evaluation of Nano-Sized Particles by Analysis of mtDNA Content and Expression Levels of Genes Required for mtDNA Maintenance: A Meta-Analysis of Pre-Clinical Studies. | Antioxidants (Basel) | 2026 | 42510579 | PubTator, text mining | PubMed |
1 to 10 of 3,065
See all 3,065 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4508
GET https://conductscience.org/api/genes/v1/4508/patents