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MT-CO1: mitochondrially encoded cytochrome c oxidase I

1 protein, 26 patents, 0 drugs, 0 trials, 6,404 NIH grants and 22,901 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMT-CO1HGNC
Namemitochondrially encoded cytochrome c oxidase IHGNC
NCBI Gene ID4512NCBI Gene
HGNC IDHGNC:7419HGNC
EnsemblENSG00000198804NCBI Gene
AliasesCOI, COX1, MTCO1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P00395Cytochrome c oxidase subunit 15133Ensembl, GeneID, HGNCUniProt

Patents 26

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19325P00395Espacenet
JP 2025529142 A2025-09-042726P00395Espacenet
US 12371689 B22025-07-292726P00395Espacenet
JP 2025032204 A2025-03-1131814P00395Espacenet
EP 4461818 A22024-11-1331814P00395Espacenet
WO 2024214081 A12024-10-17325P00395Espacenet
JP 2023058610 A2023-04-2531814P00395Espacenet
US 11446398 B22022-09-2052328P00395Espacenet
JP 2022524081 A2022-04-27155299P00395Espacenet
US 10704097 B22020-07-072P00395Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 6404

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant392,025NIH's project files
P30CA008748Cancer Center Support Grant302,025NIH's project files
P30ES013508Center of Excellence in Environmental Toxicology262,025NIH's project files
R35GM118141Mitochondrial Biogenesis in Health and Disease172,025NIH's project files
T32CA009001Program for Training in Cancer Epidemiology132,025NIH's project files
P30CA068485Cancer Center Support Grant122,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)112,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases112,025NIH's project files
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant102,025NIH's project files
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-2028102,025NIH's project files

Papers 22901

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826819PubTator, text miningPubMed
42812153PubTator, text miningPubMed
42797428PubTator, text miningPubMed
42797226PubTator, text miningPubMed
42793047PubTator, text miningPubMed
42792996PubTator, text miningPubMed
42792729PubTator, text miningPubMed
42792538PubTator, text miningPubMed
42791790PubTator, text miningPubMed
42789340PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license