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MT-CO2: mitochondrially encoded cytochrome c oxidase II

1 protein, 17 patents, 0 drugs, 0 trials, 12,323 NIH grants and 42,651 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMT-CO2HGNC
Namemitochondrially encoded cytochrome c oxidase IIHGNC
NCBI Gene ID4513NCBI Gene
HGNC IDHGNC:7421HGNC
EnsemblENSG00000198712NCBI Gene
AliasesCO2, COII, COX2, MTCO2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P00403Cytochrome c oxidase subunit 22274Ensembl, GeneID, HGNCUniProt

Patents 17

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2025535021 A2025-10-224P00403Espacenet
JP 2025529142 A2025-09-042727P00403Espacenet
US 12371689 B22025-07-292727P00403Espacenet
US 11519913 B22022-12-065P00403Espacenet
US 11446398 B22022-09-2052329P00403Espacenet
JP 2022524081 A2022-04-27155300P00403Espacenet
JP 2022511502 A2022-01-3157P00403Espacenet
KR 1020210100656 A2021-08-1728P00403Espacenet
WO 2020117952 A22020-06-1128P00403Espacenet
WO 2020043864 A12020-03-05552P00403Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 12323

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant1502,025NIH's project files
P30CA008748Cancer Center Support Grant472,025NIH's project files
P30CA068485Cancer Center Support Grant332,025NIH's project files
P30ES013508Center of Excellence in Environmental Toxicology332,025NIH's project files
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant312,025NIH's project files
P30CA047904Cancer Center Support Grant292,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases282,025NIH's project files
P30ES005022Rutgers Center for Environmental Exposure and Disease (CEED)282,025NIH's project files
P30CA006973Regional Oncology Research Center272,025NIH's project files
P30ES001247Environmental Agents as Modulators of Disease Processes262,025NIH's project files

Papers 42651

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826819PubTator, text miningPubMed
42825327PubTator, text miningPubMed
42823414PubTator, text miningPubMed
42822289PubTator, text miningPubMed
42818062PubTator, text miningPubMed
42816978PubTator, text miningPubMed
42812214PubTator, text miningPubMed
42804920PubTator, text miningPubMed
42801392PubTator, text miningPubMed
42800590PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license