Gene · 4514
MT-CO3: mitochondrially encoded cytochrome c oxidase III
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MT-CO3: mitochondrially encoded cytochrome c oxidase III. Genes, record 4514. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4514
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P00414 | Cytochrome c oxidase subunit 3 | 261 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents11
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026515744 A | 2026-05-19 | 326 | P00414 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2728 | P00414 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2728 | P00414 | Espacenet |
| WO 2024214081 A1 | 2024-10-17 | 326 | P00414 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 52330 | P00414 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 155301 | P00414 | Espacenet |
| JP 2017121240 A | 2017-07-13 | 51903 | P00414 | Espacenet |
| JP 2015518704 A | 2015-07-06 | 51903 | P00414 | Espacenet |
| EP 2803733 A1 | 2014-11-19 | 8 | P00414 | Espacenet |
| US 6489095 A | 2002-12-03 | 19 | P00414 | Espacenet |
1 to 10 of 11
See all 11 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants918
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MT-CO3 papers | Newest fiscal year |
|---|---|---|---|
| R35GM118141 | Mitochondrial Biogenesis in Health and Disease | 7 | 2025 |
| P30AG028740 | University of Florida Older Americans Independence Center (OAIC) | 5 | 2025 |
| T32ES018827 | Research Training in Environmental Toxicology | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 3 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 3 | 2025 |
| R01AI014102 | Mitochondrial DNA of Normal and Mutant Trypanosomes | 3 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 3 | 2025 |
| P30CA013696 | Cancer Center Support Grant | 2 | 2025 |
1 to 10 of 918Source NIH's project files
See all 918 nih grantsPapers2,226
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Complete mitochondrial genomics reveals phylogenetic relationships and mitogenomic features in six ectomycorrhizal Russula species. | Front Microbiol | 2026 | 42499656 | PubTator, text mining | PubMed |
| Expression and mutation characteristics of mitochondrial genes in PBMCs of SLE patients: Implications for SLE pathogenesis. | Medicine (Baltimore) | 2026 | 42470042 | PubTator, text mining | PubMed |
| Mitochondrial Genomes of Klossia Species: The First Complete Extrachromosomal Sequence Data From Parasites in the Monoxenous Apicomplexan Family Adeleidae Mesnil, 1903 (Apicomplexa: Adeleorina). | J Eukaryot Microbiol | 2026 | 42438227 | PubTator, text mining | PubMed |
| Complete Mitochondrial Genome of Ovophis makazayazaya (Viperidae, Crotalinae) and Phylogenetic Analysis. | Ecol Evol | 2026 | 42256122 | PubTator, text mining | PubMed |
| Mitogenomic characterization of Hoplia bomiensis Zeng (Coleoptera: Scarabaeidae: Melolonthinae) from Xizang, China. | Mitochondrial DNA A DNA Mapp Seq Anal | 2026 | 42253195 | PubTator, text mining | PubMed |
| Characterization of the complete mitogenomes of two phytophagous scarab beetles (Coleoptera: Scarabaeidae) and their phylogenetic implications. | Mitochondrial DNA A DNA Mapp Seq Anal | 2026 | 42246426 | PubTator, text mining | PubMed |
| Targeting Cancer Cells With Co(III)-Bipyridyl Complex: A Combined In Vitro and In Silico Study on U87MG and ME-180 Cell Lines. | Chem Biodivers | 2026 | 42216859 | PubTator, text mining | PubMed |
| Aberrant methylation of mitochondrial genes as a link between oxidative phosphorylation dysregulation and the pathogenesis of hypospadias: a multiomics and clinical sample study. | Transl Androl Urol | 2026 | 42164396 | PubTator, text mining | PubMed |
| Complex correlations between mitochondrial DNA variants and gut microbiome in major depressive disorder: a genome-wide association analysis. | BMC Psychiatry | 2026 | 42163161 | PubTator, text mining | PubMed |
| [Diagnostic value of molecular biomarkers in evaluating dental implantation results in middle-aged and elderly patients.] | Adv Gerontol | 2026 | 42150031 | PubTator, text mining | PubMed |
1 to 10 of 2,226
See all 2,226 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4514
GET https://conductscience.org/api/genes/v1/4514/patents