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Gene · 4514

MT-CO3: mitochondrially encoded cytochrome c oxidase III

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MT-CO3: mitochondrially encoded cytochrome c oxidase III. Genes, record 4514. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4514

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Gene

Symbol
MT-CO3
HGNC
Name
mitochondrially encoded cytochrome c oxidase III
HGNC
NCBI Gene ID
4514
NCBI Gene
HGNC ID
HGNC:7422
HGNC
Ensembl
ENSG00000198938
NCBI Gene
Aliases
CO3, COIII, COX3, MTCO3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P00414Cytochrome c oxidase subunit 32613Ensembl, GeneID, HGNC

Source UniProt

Patents11

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19326P00414Espacenet
JP 2025529142 A2025-09-042728P00414Espacenet
US 12371689 B22025-07-292728P00414Espacenet
WO 2024214081 A12024-10-17326P00414Espacenet
US 11446398 B22022-09-2052330P00414Espacenet
JP 2022524081 A2022-04-27155301P00414Espacenet
JP 2017121240 A2017-07-1351903P00414Espacenet
JP 2015518704 A2015-07-0651903P00414Espacenet
EP 2803733 A12014-11-198P00414Espacenet
US 6489095 A2002-12-0319P00414Espacenet

1 to 10 of 11

See all 11 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants918

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMT-CO3 papersNewest fiscal year
R35GM118141Mitochondrial Biogenesis in Health and Disease72025
P30AG028740University of Florida Older Americans Independence Center (OAIC)52025
T32ES018827Research Training in Environmental Toxicology42025
P30CA008748Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
P30CA046934University of Colorado Cancer Center Support Grant32025
P30DK063491Diabetes Research Center (DRC)32025
R01AI014102Mitochondrial DNA of Normal and Mutant Trypanosomes32025
UL1TR001863Yale Clinical and Translational Science Award32025
P30CA013696Cancer Center Support Grant22025

1 to 10 of 918Source NIH's project files

See all 918 nih grants

Papers2,226

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Complete mitochondrial genomics reveals phylogenetic relationships and mitogenomic features in six ectomycorrhizal Russula species.Front Microbiol202642499656PubTator, text miningPubMed
Expression and mutation characteristics of mitochondrial genes in PBMCs of SLE patients: Implications for SLE pathogenesis.Medicine (Baltimore)202642470042PubTator, text miningPubMed
Mitochondrial Genomes of Klossia Species: The First Complete Extrachromosomal Sequence Data From Parasites in the Monoxenous Apicomplexan Family Adeleidae Mesnil, 1903 (Apicomplexa: Adeleorina).J Eukaryot Microbiol202642438227PubTator, text miningPubMed
Complete Mitochondrial Genome of Ovophis makazayazaya (Viperidae, Crotalinae) and Phylogenetic Analysis.Ecol Evol202642256122PubTator, text miningPubMed
Mitogenomic characterization of Hoplia bomiensis Zeng (Coleoptera: Scarabaeidae: Melolonthinae) from Xizang, China.Mitochondrial DNA A DNA Mapp Seq Anal202642253195PubTator, text miningPubMed
Characterization of the complete mitogenomes of two phytophagous scarab beetles (Coleoptera: Scarabaeidae) and their phylogenetic implications.Mitochondrial DNA A DNA Mapp Seq Anal202642246426PubTator, text miningPubMed
Targeting Cancer Cells With Co(III)-Bipyridyl Complex: A Combined In Vitro and In Silico Study on U87MG and ME-180 Cell Lines.Chem Biodivers202642216859PubTator, text miningPubMed
Aberrant methylation of mitochondrial genes as a link between oxidative phosphorylation dysregulation and the pathogenesis of hypospadias: a multiomics and clinical sample study.Transl Androl Urol202642164396PubTator, text miningPubMed
Complex correlations between mitochondrial DNA variants and gut microbiome in major depressive disorder: a genome-wide association analysis.BMC Psychiatry202642163161PubTator, text miningPubMed
[Diagnostic value of molecular biomarkers in evaluating dental implantation results in middle-aged and elderly patients.]Adv Gerontol202642150031PubTator, text miningPubMed

1 to 10 of 2,226

See all 2,226 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4514

GET https://conductscience.org/api/genes/v1/4514/patents