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MT-CYB: mitochondrially encoded cytochrome b

1 protein, 12 patents, 0 drugs, 0 trials, 2,312 NIH grants and 8,066 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMT-CYBHGNC
Namemitochondrially encoded cytochrome bHGNC
NCBI Gene ID4519NCBI Gene
HGNC IDHGNC:7427HGNC
EnsemblENSG00000198727NCBI Gene
AliasesCOB, CYTB, MTCYB, UQCR3NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P00156Cytochrome b3805Ensembl, GeneID, HGNCUniProt

Patents 12

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19327P00156Espacenet
JP 2025529142 A2025-09-042729P00156Espacenet
US 12371689 B22025-07-292729P00156Espacenet
WO 2024214081 A12024-10-17327P00156Espacenet
US 11446398 B22022-09-2052327P00156Espacenet
JP 2022524081 A2022-04-27155298P00156Espacenet
JP 2022511502 A2022-01-3154P00156Espacenet
KR 1020210100656 A2021-08-1722P00156Espacenet
WO 2020117952 A22020-06-1122P00156Espacenet
JP 2017121240 A2017-07-1351900P00156Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2312

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30DK020572Michigan Diabetes Research Center (MDRC)102,025NIH's project files
P30AI045008Penn Center for AIDS Research72,025NIH's project files
P30CA008748Cancer Center Support Grant72,025NIH's project files
R01EY010804Setting the Stage for Replacement of Mitochondrial Genes72,025NIH's project files
P30CA016672Cancer Center Support Grant62,025NIH's project files
U19AI089680Harnessing Innovation to Transform Malaria Surveillance into Key Interventions Across Transmission Settings in Zambia62,025NIH's project files
ZIABC010319Structural Basis of Biological Membrane Protein Functions and Drug Resistance62,025NIH's project files
R35GM118141Mitochondrial Biogenesis in Health and Disease52,025NIH's project files
T32AI007417The Molecular and Cellular Basis of Infectious Diseases (MCBID) Program52,025NIH's project files
U54MD007601Ola HAWAII52,025NIH's project files

Papers 8066

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818469PubTator, text miningPubMed
42773970PubTator, text miningPubMed
42772623PubTator, text miningPubMed
42719737PubTator, text miningPubMed
42683731PubTator, text miningPubMed
42679026PubTator, text miningPubMed
42640698PubTator, text miningPubMed
42599909PubTator, text miningPubMed
42591879PubTator, text miningPubMed
42561453PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license