Gene · 4522
Papers1,437
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
41 to 60 of 1,437
Download this page as JSON| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Hit to lead optimization of isopentenyl chalcones as novel MTHFD2 inhibitors for cancer treatment: design, synthesis, in-vitro, in-vivo and in-silico studies. | Eur J Med Chem | 2025 | 40334504 | PubTator, text mining | PubMed |
| Xenobiotic metabolizing gene variants and the risk of male infertility - A systematic review, meta-analysis and in silico analysis. | Toxicol Rep | 2025 | 40271533 | PubTator, text mining | PubMed |
| A new paradigm for drug discovery in the treatment of complex diseases: drug discovery and optimization. | Chin Med | 2025 | 40122800 | PubTator, text mining | PubMed |
| Identification of genetic variants in MTHFD1 associated with risk of hypertension. | Gene | 2025 | 39914793 | PubTator, text mining | PubMed |
| Association of MTHFD1 G1958A (rs2236225) gene polymorphism with the risk of congenital heart disease: a systematic review and meta-analysis. | BMC Med Genomics | 2025 | 39871280 | PubTator, text mining | PubMed |
| Meta-analysis and systematic review for the genetic basis of cleft lip and palate. | J Oral Biol Craniofac Res | 2025 | 39866383 | PubTator, text mining | PubMed |
| Identifying MTHFD1 and LGALS4 as Potential Therapeutic Targets in Prostate Cancer Through Multi-Omics Mendelian Randomization Analysis. | Biomedicines | 2025 | 39857769 | PubTator, text mining | PubMed |
| Evaluating toxicity and level of DNA damage in human fetal lung cells upon exposure to 5-methyltetrahydrofolate (bioactive folate). | Nutr Health | 2025 | 39692323 | PubTator, text mining | PubMed |
| Evidence for interaction of 5,10-methylenetetrahydrofolate reductase (MTHFR) with methylenetetrahydrofolate dehydrogenase (MTHFD1) and general control nonderepressible 1 (GCN1). | Biochimie | 2025 | 39571719 | PubTator, text mining | PubMed |
| Betaine and B12 Intake, Glutathione Concentration, and MTHFR, PEMT, and MTHFD1 Genotypes Are Associated with Diabetes-Related Parameters in Polish Adults. | J Nutr | 2025 | 39442756 | PubTator, text mining | PubMed |
| Development of Potent and Selective Inhibitors of Methylenetetrahydrofolate Dehydrogenase 2 for Targeting Acute Myeloid Leukemia: SAR, Structural Insights, and Biological Characterization. | J Med Chem | 2024 | 39591507 | PubTator, text mining | PubMed |
| MTHFD1 Regulates Autophagy to Promote Growth and Metastasis in Colorectal Cancer via the PI3K-AKT-mTOR Signaling Pathway. | Cancer Med | 2024 | 39571599 | PubTator, text mining | PubMed |
| Selectivity analysis of diaminopyrimidine-based inhibitors of MTHFD1, MTHFD2 and MTHFD2L. | Sci Rep | 2024 | 39256448 | PubTator, text mining | PubMed |
| Specific association of MTHFD1 expressions with small cell lung cancer development and chemoradiotherapy outcome. | Saudi Med J | 2024 | 39074897 | PubTator, text mining | PubMed |
| Congenital Heart Disease and Genetic Changes in Folate/Methionine Cycles. | Genes (Basel) | 2024 | 39062651 | PubTator, text mining | PubMed |
| Thermostability-assisted limited proteolysis-coupled mass spectrometry for capturing drug target proteins and sites. | Anal Chim Acta | 2024 | 38834267 | PubTator, text mining | PubMed |
| Detection of differential bait proteoforms through immunoprecipitation-mass spectrometry data analysis. | Sci Data | 2024 | 38811611 | PubTator, text mining | PubMed |
Choline metabolism reprogramming mediates an immunosuppressive microenvironment in non-small cell lung cancer (NSCLC) by promoting tumor-associated macrophage functional polarization and endothelial cell proliferation. | J Transl Med | 2024 | 38730286 | PubTator, text mining | PubMed |
| MTHFD2-mediated redox homeostasis promotes gastric cancer progression under hypoxic conditions. | Redox Rep | 2024 | 38723197 | PubTator, text mining | PubMed |
| Cycling back to folate metabolism in cancer. | Nat Cancer | 2024 | 38698089 | PubTator, text mining | PubMed |
gene-search-2026-11-11-0.2.0
Sources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
Twenty rows a page, as JSON. No key.
GET https://conductscience.org/api/genes/v1/4522/papers?page=3