ConductScience.org, home

Gene · 4536

MT-ND2: mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. MT-ND2: mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2. Genes, record 4536. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4536

On this page

Gene

Symbol
MT-ND2
HGNC
Name
mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2
HGNC
NCBI Gene ID
4536
NCBI Gene
HGNC ID
HGNC:7456
HGNC
Ensembl
ENSG00000198763
NCBI Gene
Aliases
MTND2, NAD2, ND2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P03891NADH-ubiquinone oxidoreductase chain 23477Ensembl, GeneID, HGNC

Source UniProt

Patents16

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19317P03891Espacenet
JP 2025529142 A2025-09-042731P03891Espacenet
US 12371689 B22025-07-292731P03891Espacenet
WO 2024214081 A12024-10-17317P03891Espacenet
US 11446398 B22022-09-2052332P03891Espacenet
JP 2022524081 A2022-04-27155303P03891Espacenet
WO 2020043864 A12020-03-051693P03891Espacenet
US 9073976 B22015-07-0760P03891Espacenet
EP 2803733 A12014-11-193P03891Espacenet
US 8859500 B22014-10-149P03891Espacenet

1 to 10 of 16

See all 16 patents

Drugs4

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ME-344CHEMBL5314386Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL
METFORMINCHEMBL1431Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL
METFORMIN HYDROCHLORIDECHEMBL1703Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL
NV-128CHEMBL3545135Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL

Trials1,218

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants1,226

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMT-ND2 papersNewest fiscal year
P30MH062512HIV Neurobehavioral Research Center72025
P30AI036214San Diego Center for AIDS Research (SD CFAR)52025
P30CA016086Cancer Center Support Grant52025
P30CA016672Cancer Center Support Grant42025
R25MH081482Interdisciplinary Research Fellowship in NeuroAIDS42025
P30AG028740University of Florida Older Americans Independence Center (OAIC)32025
P30CA071789University of Hawaii Cancer Center CCSG32025
P30CA168524The University of Kansas Cancer Center32025
P30MH075673JHU Center for the Advancement of HIV Neurotherapeutics (JHU CAHN)32025
R01CA159859Dysregulation of the Core Binding Factor Complex Inhibits Differentiation and Drives Group 4 Medulloblastoma32025

1 to 10 of 1,226Source NIH's project files

See all 1,226 nih grants

Papers2,405

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The first two complete mitochondrial genomes for the genus Neotrichoporoides (Hymenoptera, Eulophidae) and their phylogenetic analysis.Zookeys202642732344PubTator, text miningPubMed
A new species of Heremites Gray, 1845 (Squamata, Scincidae) from the transboundary Hindu Kush foothills.Zookeys202642732331PubTator, text miningPubMed
Fructose induces PERK-dependent ER stress and mitochondrial dysfunction via nucleotide depletion in clear cell renal cell carcinoma.Cell Death Dis202642675041PubTator, text miningPubMed
Phase-dependent dynamics of circulating cell-free mitochondrial DNA reflect distinct immunometabolic states.Rev Inst Med Trop Sao Paulo202642525119PubTator, text miningPubMed
Description of a New Species of Cyrtodactylus (Squamata: Gekkonidae) from Eastern Nepal.Zootaxa202642408908PubTator, text miningPubMed
A new species of Cyrtodactylus Gray, 1827 (Reptilia: Squamata: Gekkonidae) from Kokrajhar District, Assam, India.Zootaxa202642408578PubTator, text miningPubMed
Morphological and genetic evidence support new species of Stenocercus (Iguania: Tropiduridae) from the Peruvian Andes.Zootaxa202642408508PubTator, text miningPubMed
Confirmed occurrence and DNA barcoding of the Indo-Pacific Slender Gecko, Hemiphyllodactylus typus Bleeker, 1860 (Squamata, Gekkonidae) in Vietnam.Zootaxa202642408452PubTator, text miningPubMed
PCR-based species identification tools for wireworms (Coleoptera: Elateridae) of economic importance in Canada.Pest Manag Sci202642348270PubTator, text miningPubMed
Complete Mitochondrial Genome of Ovophis makazayazaya (Viperidae, Crotalinae) and Phylogenetic Analysis.Ecol Evol202642256122PubTator, text miningPubMed

1 to 10 of 2,405

See all 2,405 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4536

GET https://conductscience.org/api/genes/v1/4536/patents