Gene · 4549
MT-RNR1: mitochondrially encoded 12S rRNA
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MT-RNR1: mitochondrially encoded 12S rRNA. Genes, record 4549. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4549
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| A0A0C5B5G6 | Mitochondrial-derived peptide MOTS-c | 16 | 0 | HGNC |
Source UniProt
Patents110
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| US 12064467 B2 | 2024-08-20 | 5 | A0A0C5B5G6 | Espacenet |
| US 11753445 B2 | 2023-09-12 | 2 | A0A0C5B5G6 | Espacenet |
| US 11753445 B2 | 2023-09-12 | 3 | A0A0C5B5G6 | Espacenet |
| US 11753445 B2 | 2023-09-12 | 4 | A0A0C5B5G6 | Espacenet |
| US 11753445 B2 | 2023-09-12 | 5 | A0A0C5B5G6 | Espacenet |
| US 11753445 B2 | 2023-09-12 | 69 | A0A0C5B5G6 | Espacenet |
| US 11753445 B2 | 2023-09-12 | 70 | A0A0C5B5G6 | Espacenet |
| US 11753445 B2 | 2023-09-12 | 71 | A0A0C5B5G6 | Espacenet |
| US 11753445 B2 | 2023-09-12 | 72 | A0A0C5B5G6 | Espacenet |
| US 11753445 B2 | 2023-09-12 | 103 | A0A0C5B5G6 | Espacenet |
1 to 10 of 110
See all 110 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants556
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MT-RNR1 papers | Newest fiscal year |
|---|---|---|---|
| R01DC012049 | Optimizing Genetic Testing for Deafness for Clinical Diagnostics | 7 | 2025 |
| R01DC009645 | A Collaborative Search for New Genes for Non-Syndromic Deafness | 6 | 2025 |
| U24HG010615 | PharmGKB | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 4 | 2025 |
| U54CA233465 | 3/3 Florida-California Cancer Research, Education and Engagement (CaRE2) Health Center | 3 | 2025 |
| K08DC019716 | Spiral Ganglion Health: from Genomics to Gene Therapy | 2 | 2025 |
| K24HL133373 | Discovery, Implementation and Mentorship in Personalized Cardiovascular Pharmacotherapy | 2 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 2 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 2 | 2025 |
1 to 10 of 556Source NIH's project files
See all 556 nih grantsPapers1,299
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| digitalMLPA EZtec-MS: A new highly multiplexed DNA probe-based technique for neonatal screening. | Eur J Hum Genet | 2026 | 42773160 | PubTator, text mining | PubMed |
| Mutation Spectrum and Novel Rare Variants in a Han Chinese Hearing Loss Cohort Using a Tiered Sequencing Strategy. | Mol Genet Genomic Med | 2026 | 42764263 | PubTator, text mining | PubMed |
| Novel Variants in Mitochondrial Ribosomal RNA Genes MT-RNR1 and MT-RNR2 Identified in Hereditary Optic Neuropathy Initially Presenting as Normal Tension Glaucoma: A Case Report. | Case Rep Ophthalmol | 2026 | 42622002 | PubTator, text mining | PubMed |
| MT-RNR1 genotype testing for preventing aminoglycoside-mediated ototoxicity: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI-PGx). | Br J Clin Pharmacol | 2026 | 42524757 | PubTator, text mining | PubMed |
| Managing Secondary Findings from Germline Pharmacogenomic Testing. | J Pers Med | 2026 | 42506114 | PubTator, text mining | PubMed |
| A large-scale multi-ancestry mitochondrial variant association analysis for cardiometabolic traits. | Nat Commun | 2026 | 42401575 | PubTator, text mining | PubMed |
| Mechanisms, prevention, and management of aminoglycoside-induced hearing loss in neonates and children: a translational review. | Front Pharmacol | 2026 | 42358372 | PubTator, text mining | PubMed |
| Genetic Diagnosis of Non-Syndromic Hearing Loss in South Indian Consanguineous Families Using Whole-Exome Sequencing. | Medicina (Kaunas) | 2026 | 42356053 | PubTator, text mining | PubMed |
| Genetic Landscape of Hearing Loss in Brazilian Patients Reveals Population-Specific Variants and Clinical Correlations. | Clin Genet | 2026 | 42233699 | PubTator, text mining | PubMed |
| MOTS-c, a mitochondrial-derived peptide, ameliorates lysosomal membrane permeability and improves survival of soft tissue transplantation. | Autophagy | 2026 | 42153537 | PubTator, text mining | PubMed |
1 to 10 of 1,299
See all 1,299 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4549
GET https://conductscience.org/api/genes/v1/4549/patents?page=2