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MUC1: mucin 1, cell surface associated

1 protein, 194 patents, 16 drugs, 20 trials, 6,667 NIH grants and 36,545 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMUC1HGNC
Namemucin 1, cell surface associatedHGNC
NCBI Gene ID4582NCBI Gene
HGNC IDHGNC:7508HGNC
EnsemblENSG00000185499NCBI Gene
AliasesADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUMNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P15941Mucin-11,25523Ensembl, GeneID, HGNCUniProt

Patents 194

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4830734 A12026-10-2824P15941Espacenet
US 12653852 B22026-06-1644P15941Espacenet
JP 2026510624 A2026-04-10129P15941Espacenet
JP 2026509869 A2026-03-2534P15941Espacenet
WO 2026054037 A2026-03-12138P15941Espacenet
WO 2026054039 A2026-03-12137P15941Espacenet
EP 4705273 A22026-03-11461P15941Espacenet
JP 2026507191 A2026-02-271P15941Espacenet
JP 2026506240 A2026-02-201P15941Espacenet
JP 2026505699 A2026-02-1850P15941Espacenet

Drugs 16

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
AR-20.5CHEMBL2109364Mucin-1 otherOTHERChEMBL
AS-1403CHEMBL2109360Mucin-1 binding agentBINDING AGENTChEMBL
CANTUZUMAB MERTANSINECHEMBL1742997Mucin-1 binding agentBINDING AGENTChEMBL
CANTUZUMAB RAVTANSINECHEMBL1742998Mucin-1 binding agentBINDING AGENTChEMBL
CMB-401CHEMBL2109284Mucin-1 binding agentBINDING AGENTChEMBL
EPITUMOMABCHEMBL2108403Mucin-1 binding agentBINDING AGENTChEMBL
EPITUMOMAB CITUXETANCHEMBL2108592Mucin-1 binding agentBINDING AGENTChEMBL
GATIPOTUZUMABCHEMBL4297560Mucin-1 inhibitorINHIBITORChEMBL
HUHMFG1CHEMBL2109637Mucin-1 otherOTHERChEMBL
HUPAM4CHEMBL2109365Mucin-1 binding agentBINDING AGENTChEMBL

Trials 20

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT03360734GATIPOTUZUMABPHASE1ClinicalTrials.gov
NCT02984683SAR-566658PHASE22021-09-08ClinicalTrials.gov
NCT02049151TECEMOTIDEPHASE32017-03-30ClinicalTrials.gov
NCT01899599GATIPOTUZUMABPHASE2ClinicalTrials.gov
NCT01507103TECEMOTIDEPHASE22016-06-02ClinicalTrials.gov
NCT01496131TECEMOTIDEPHASE22018-03-09ClinicalTrials.gov
NCT01462513TECEMOTIDEPHASE2ClinicalTrials.gov
NCT01222624GATIPOTUZUMABPHASE1ClinicalTrials.gov
NCT01094548TECEMOTIDEPHASE22016-02-22ClinicalTrials.gov
NCT01015443TECEMOTIDEPHASE32016-08-02ClinicalTrials.gov

NIH grants 6667

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant2072,025NIH's project files
R01CA097098Targeting the MUC1-C Oncoprotein in Triple-Negative Breast Cancer1132,025NIH's project files
P30CA016672Cancer Center Support Grant872,025NIH's project files
P30CA006973Regional Oncology Research Center612,025NIH's project files
P30CA036727Buffett Cancer Center Support Grant582,025NIH's project files
P50CA217694SPORE in Soft Tissue Sarcoma402,025NIH's project files
U01CA200466Validation of biomarkers for risk prediction and early diagnosis of Pancreatic Adenocarcinoma332,025NIH's project files
P30CA047904Cancer Center Support Grant322,025NIH's project files
ZIABC010666Cancer Immunotherapy302,025NIH's project files
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant262,025NIH's project files

Papers 36545

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822259PubTator, text miningPubMed
42822009PubTator, text miningPubMed
42819945PubTator, text miningPubMed
42819555PubTator, text miningPubMed
42814626PubTator, text miningPubMed
42812488PubTator, text miningPubMed
42812136PubTator, text miningPubMed
42810004PubTator, text miningPubMed
42808692PubTator, text miningPubMed
42804014PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license