ConductScience.org, home

Library / Genes

MUC5AC: mucin 5AC, oligomeric mucus/gel-forming

1 protein, 34 patents, 3 drugs, 5 trials, 3,620 NIH grants and 9,642 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMUC5ACHGNC
Namemucin 5AC, oligomeric mucus/gel-formingHGNC
NCBI Gene ID4586NCBI Gene
HGNC IDHGNC:7515HGNC
EnsemblENSG00000215182NCBI Gene
AliasesMUC5, TBM, leB, mucinNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P98088Mucin-5AC5,65414Ensembl, GeneID, HGNCUniProt

Patents 34

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1918959P98088Espacenet
JP 2025166836 A2025-11-0628P98088Espacenet
EP 4641201 A22025-10-2923667P98088Espacenet
JP 2025147176 A2025-10-069105P98088Espacenet
JP 2025147176 A2025-10-0614689P98088Espacenet
JP 2025517969 A2025-06-1223667P98088Espacenet
JP 2025517970 A2025-06-1218959P98088Espacenet
JP 2025028160 A2025-02-289105P98088Espacenet
JP 2025028160 A2025-02-2814689P98088Espacenet
KR 1020250010750 A2025-01-219105P98088Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
CLIVATUZUMAB TETRAXETANCHEMBL3301586Mucin-5AC binding agentBINDING AGENTChEMBL
ENSITUXIMABCHEMBL1743013Mucin-5AC otherOTHERChEMBL
YTTRIUM Y 90 CLIVATUZUMAB TETRAXETANCHEMBL2108708Mucin-5AC binding agentBINDING AGENTChEMBL

Trials 5

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT01956812CLIVATUZUMAB TETRAXETANPHASE3ClinicalTrials.gov
NCT01834235ENSITUXIMABPHASE1/PHASE22025-05-07ClinicalTrials.gov
NCT01510561CLIVATUZUMAB TETRAXETANPHASE1ClinicalTrials.gov
NCT01040000ENSITUXIMABPHASE1/PHASE2ClinicalTrials.gov
NCT00603863YTTRIUM Y 90 CLIVATUZUMAB TETRAXETANPHASE1/PHASE2ClinicalTrials.gov

NIH grants 3620

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30DK065988UNC Cystic Fibrosis Research and Translation Core Center482,025NIH's project files
P30CA008748Cancer Center Support Grant302,025NIH's project files
U01CA200466Validation of biomarkers for risk prediction and early diagnosis of Pancreatic Adenocarcinoma272,025NIH's project files
P30CA016672Cancer Center Support Grant262,025NIH's project files
P30DK054759Precision Medicine Center for Cystic Fibrosis222,025NIH's project files
P30CA036727Buffett Cancer Center Support Grant212,025NIH's project files
P30DK058404Molecular and Cellular Basis for Digestive Diseases192,025NIH's project files
R01HL080396Role of mucin in lung homeostasis and pathophysiology192,025NIH's project files
U01CA210240Pancreatic Cancer Detection Consortium192,025NIH's project files
P30DK056338Texas Medical Center Digestive Diseases Center182,025NIH's project files

Papers 9642

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818841PubTator, text miningPubMed
42810655PubTator, text miningPubMed
42808463PubTator, text miningPubMed
42805313PubTator, text miningPubMed
42773388PubTator, text miningPubMed
42750737PubTator, text miningPubMed
42750238PubTator, text miningPubMed
42737845PubTator, text miningPubMed
42730417PubTator, text miningPubMed
42725321PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license