Gene · 4591
TRIM37: tripartite motif containing 37
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. TRIM37: tripartite motif containing 37. Genes, record 4591. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4591
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O94972 | E3 ubiquitin-protein ligase TRIM37 | 964 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents32
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 68068 | O94972 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 68071 | O94972 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2048 | O94972 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 11400 | O94972 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1611 | O94972 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1611 | O94972 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 11400 | O94972 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2048 | O94972 | Espacenet |
| JP 2024161501 A | 2024-11-19 | 74 | O94972 | Espacenet |
| KR 1020240108531 A | 2024-07-09 | 74 | O94972 | Espacenet |
1 to 10 of 32
See all 32 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants974
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | TRIM37 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 12 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30AI050410 | The University of North Carolina Center for AIDS Research | 5 | 2025 |
| R01GM074207 | Analysis of Centrosome Dynamics | 5 | 2025 |
| U10CA180886 | COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement | 5 | 2025 |
| U10CA180899 | Children's Oncology Group Statistics and Data Center | 5 | 2025 |
| P30AI050409 | Center for AIDS Research at Emory University | 4 | 2025 |
| P30AI027767 | UAB Center for AIDS Research (CFAR) | 3 | 2025 |
| P30DK040561 | Boston Area Nutrition Obesity Research Center (NORC) | 3 | 2025 |
| P51OD011132 | Emory National Primate Research Center | 3 | 2025 |
1 to 10 of 974Source NIH's project files
See all 974 nih grantsPapers1,564
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Design, Synthesis, and Biological Activity Evaluation of Quinazoline-Based PLK4 Inhibitors. | Biomedicines | 2026 | 42652193 | PubTator, text mining | PubMed |
| Genome-wide association study of egg numbers across different laying phases in a large-scale layer population. | Br Poult Sci | 2026 | 42615881 | PubTator, text mining | PubMed |
| TRIM37 interacts with TRIM28 to maintain primordial germ cell identity during migration. | Cell Res | 2026 | 42533095 | PubTator, text mining | PubMed |
| The METTL3/TRIM37 axis contributes to the progression of non-alcoholic fatty liver disease by promoting CAV1 degradation. | Mol Cell Biochem | 2026 | 42484789 | PubTator, text mining | PubMed |
| Discovery of ZSL-M028: A Potent, Selective and Orally Available Quinazoline-Based PLK4 Inhibitor Targeting TRIM37-Amplified Neuroblastoma. | J Med Chem | 2026 | 42463132 | PubTator, text mining | PubMed |
| A simple and versatile fluorescence-based method to enhance prime editing in human pluripotent stem cells. | BMC Methods | 2026 | 42453142 | PubTator, text mining | PubMed |
| DHODH Drives Sunitinib Resistance Via a Non-Enzymatic Mechanism by Inhibiting TRIM28 Ubiquitination and Consequent VEGFA Activation in RCC. | Adv Sci (Weinh) | 2026 | 42335405 | PubTator, text mining | PubMed |
| Combined inhibition of PLK4 and PPM1D promotes cell death in cancer cells with 17q amplification. | Cancer Cell Int | 2026 | 42316241 | PubTator, text mining | PubMed |
| TRIM37 interacts with PTEN to promote progression of hepatocellular carcinoma cells by modulating AKT/GSK-3β/β-Catenin pathway. | Transl Cancer Res | 2026 | 42305509 | PubTator, text mining | PubMed |
| PFN1 inhibits lytic replication of Kaposi sarcoma-associated herpesvirus through SQSTM1/p62-mediated selective autophagy targeting the KSHV helicase. | Autophagy | 2026 | 42260986 | PubTator, text mining | PubMed |
1 to 10 of 1,564
See all 1,564 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4591
GET https://conductscience.org/api/genes/v1/4591/patents?page=2