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Gene · 4591

TRIM37: tripartite motif containing 37

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. TRIM37: tripartite motif containing 37. Genes, record 4591. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4591

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Gene

Symbol
TRIM37
HGNC
Name
tripartite motif containing 37
HGNC
NCBI Gene ID
4591
NCBI Gene
HGNC ID
HGNC:7523
HGNC
Ensembl
ENSG00000108395
NCBI Gene
Aliases
KIAA0898, MUL, POB1, TEF3
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O94972E3 ubiquitin-protein ligase TRIM379641Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1468068O94972Espacenet
JP 2026004568 A2026-01-1468071O94972Espacenet
EP 4650780 A22025-11-192048O94972Espacenet
EP 4641201 A22025-10-2911400O94972Espacenet
EP 4641201 A22025-10-291611O94972Espacenet
JP 2025517969 A2025-06-121611O94972Espacenet
JP 2025517969 A2025-06-1211400O94972Espacenet
JP 2025517970 A2025-06-122048O94972Espacenet
JP 2024161501 A2024-11-1974O94972Espacenet
KR 1020240108531 A2024-07-0974O94972Espacenet

1 to 10 of 32

See all 32 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants974

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleTRIM37 papersNewest fiscal year
P30CA016672Cancer Center Support Grant122025
P30CA008748Cancer Center Support Grant62025
P30AI050410The University of North Carolina Center for AIDS Research52025
R01GM074207Analysis of Centrosome Dynamics52025
U10CA180886COG NCTN Network Group Operations Center - Year 11 STAR Act MCI and PEC Supplement52025
U10CA180899Children's Oncology Group Statistics and Data Center52025
P30AI050409Center for AIDS Research at Emory University42025
P30AI027767UAB Center for AIDS Research (CFAR)32025
P30DK040561Boston Area Nutrition Obesity Research Center (NORC)32025
P51OD011132Emory National Primate Research Center32025

1 to 10 of 974Source NIH's project files

See all 974 nih grants

Papers1,564

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Design, Synthesis, and Biological Activity Evaluation of Quinazoline-Based PLK4 Inhibitors.Biomedicines202642652193PubTator, text miningPubMed
Genome-wide association study of egg numbers across different laying phases in a large-scale layer population.Br Poult Sci202642615881PubTator, text miningPubMed
TRIM37 interacts with TRIM28 to maintain primordial germ cell identity during migration.Cell Res202642533095PubTator, text miningPubMed
The METTL3/TRIM37 axis contributes to the progression of non-alcoholic fatty liver disease by promoting CAV1 degradation.Mol Cell Biochem202642484789PubTator, text miningPubMed
Discovery of ZSL-M028: A Potent, Selective and Orally Available Quinazoline-Based PLK4 Inhibitor Targeting TRIM37-Amplified Neuroblastoma.J Med Chem202642463132PubTator, text miningPubMed
A simple and versatile fluorescence-based method to enhance prime editing in human pluripotent stem cells.BMC Methods202642453142PubTator, text miningPubMed
DHODH Drives Sunitinib Resistance Via a Non-Enzymatic Mechanism by Inhibiting TRIM28 Ubiquitination and Consequent VEGFA Activation in RCC.Adv Sci (Weinh)202642335405PubTator, text miningPubMed
Combined inhibition of PLK4 and PPM1D promotes cell death in cancer cells with 17q amplification.Cancer Cell Int202642316241PubTator, text miningPubMed
TRIM37 interacts with PTEN to promote progression of hepatocellular carcinoma cells by modulating AKT/GSK-3β/β-Catenin pathway.Transl Cancer Res202642305509PubTator, text miningPubMed
PFN1 inhibits lytic replication of Kaposi sarcoma-associated herpesvirus through SQSTM1/p62-mediated selective autophagy targeting the KSHV helicase.Autophagy202642260986PubTator, text miningPubMed

1 to 10 of 1,564

See all 1,564 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4591

GET https://conductscience.org/api/genes/v1/4591/patents?page=2