Gene · 4593
MUSK: muscle associated receptor tyrosine kinase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MUSK: muscle associated receptor tyrosine kinase. Genes, record 4593. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4593
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O15146 | Muscle, skeletal receptor tyrosine-protein kinase | 869 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents49
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026152042 A1 | 2026-07-16 | 1 | O15146 | Espacenet |
| JP 2026056615 A | 2026-04-01 | 129 | O15146 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 54214 | O15146 | Espacenet |
| JP 2025541179 A | 2025-12-18 | 28 | O15146 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 9467 | O15146 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 9719 | O15146 | Espacenet |
| EP 4630459 A1 | 2025-10-15 | 28 | O15146 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2756 | O15146 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2756 | O15146 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 9719 | O15146 | Espacenet |
1 to 10 of 49
See all 49 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants922
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MUSK papers | Newest fiscal year |
|---|---|---|---|
| R01AI114780 | Mechanisms of autoimmunity in myasthenia gravis | 19 | 2025 |
| U54NS115054 | Rare Disease Network for Myasthenia Gravis | 19 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 10 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 5 | 2025 |
| T32MH020068 | Interdisciplinary Predoctoral Neuroscience Training Program in the Neuroscience Graduate Program. | 5 | 2025 |
| T32AG041688 | Brown University Training Program in the Molecular Biology of Aging | 4 | 2025 |
| U2CTR002818 | Data Management and Coordinating Center: Rare Diseases Clinical Research Network | 4 | 2025 |
| P30AI064518 | Center for AIDS Research | 3 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 922Source NIH's project files
See all 922 nih grantsPapers3,141
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Apheresis-Triggered Torsades De Pointes in Congenital Long QT Syndrome Type 2: Citrate-Related Arrhythmia Risk and Safe Modality Switching During Myasthenic Crisis. | J Clin Apher | 2026 | 42817013 | PubTator, text mining | PubMed |
| Rozanolixizumab: A Review in AChR or MuSK Autoantibody-Positive Generalised Myasthenia Gravis. | CNS Drugs | 2026 | 42814271 | PubTator, text mining | PubMed |
| Very Late-Onset Myasthenia Gravis in a Very Elderly Patient: Diagnostic Challenges and Importance of Early Recognition. | Geriatrics (Basel) | 2026 | 42776710 | PubTator, text mining | PubMed |
| Crk/Crk-L-mediated Rapgef1 recruitment couples MuSK signaling to AChR anchoring at the neuromuscular junction. | Cell Chem Biol | 2026 | 42772281 | PubTator, text mining | PubMed |
| Digital assessment in myasthenia gravis: evidence, validation, and a proposed framework for autoimmune heterogeneity, remote monitoring, and clinical endpoints. | Front Immunol | 2026 | 42756700 | PubTator, text mining | PubMed |
| A case report of sequential efgartigimod and rituximab treatment for tSNMG. | Front Immunol | 2026 | 42755762 | PubTator, text mining | PubMed |
| [A differentiated approach to thymectomy in generalized form of myasthenia gravis]. | Khirurgiia (Mosk) | 2026 | 42735009 | PubTator, text mining | PubMed |
| TUBA4A Pathogenic Variant Manifesting With Adulthood-Onset Genetic Myasthenic Syndrome, Myopathy, and Infertility. | Eur J Neurol | 2026 | 42725680 | PubTator, text mining | PubMed |
| Motor unit number index (MUNIX) in myasthenia gravis: A cross-sectional pilot sudy. | J Electromyogr Kinesiol | 2026 | 42721533 | PubTator, text mining | PubMed |
| Efgartigimod and Steroid Pulse Therapy as an Early Fast-acting Treatment Strategy for Anti-MUSK Myasthenic Crisis. | Intern Med | 2026 | 42716742 | PubTator, text mining | PubMed |
1 to 10 of 3,141
See all 3,141 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4593
GET https://conductscience.org/api/genes/v1/4593/patents?page=2