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Gene · 4593

MUSK: muscle associated receptor tyrosine kinase

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MUSK: muscle associated receptor tyrosine kinase. Genes, record 4593. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4593

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Gene

Symbol
MUSK
HGNC
Name
muscle associated receptor tyrosine kinase
HGNC
NCBI Gene ID
4593
NCBI Gene
HGNC ID
HGNC:7525
HGNC
Ensembl
ENSG00000030304
NCBI Gene
Aliases
CMS9, FADS
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O15146Muscle, skeletal receptor tyrosine-protein kinase8694Ensembl, GeneID, HGNC

Source UniProt

Patents49

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026152042 A12026-07-161O15146Espacenet
JP 2026056615 A2026-04-01129O15146Espacenet
JP 2026004568 A2026-01-1454214O15146Espacenet
JP 2025541179 A2025-12-1828O15146Espacenet
EP 4650780 A22025-11-199467O15146Espacenet
EP 4641201 A22025-10-299719O15146Espacenet
EP 4630459 A12025-10-1528O15146Espacenet
JP 2025529142 A2025-09-042756O15146Espacenet
US 12371689 B22025-07-292756O15146Espacenet
JP 2025517969 A2025-06-129719O15146Espacenet

1 to 10 of 49

See all 49 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants922

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMUSK papersNewest fiscal year
R01AI114780Mechanisms of autoimmunity in myasthenia gravis192025
U54NS115054Rare Disease Network for Myasthenia Gravis192025
UL1TR001863Yale Clinical and Translational Science Award102025
P30CA008748Cancer Center Support Grant62025
P30CA016087Cancer Center Support Grant52025
T32MH020068Interdisciplinary Predoctoral Neuroscience Training Program in the Neuroscience Graduate Program.52025
T32AG041688Brown University Training Program in the Molecular Biology of Aging42025
U2CTR002818Data Management and Coordinating Center: Rare Diseases Clinical Research Network42025
P30AI064518Center for AIDS Research32025
P30CA016672Cancer Center Support Grant32025

1 to 10 of 922Source NIH's project files

See all 922 nih grants

Papers3,141

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Apheresis-Triggered Torsades De Pointes in Congenital Long QT Syndrome Type 2: Citrate-Related Arrhythmia Risk and Safe Modality Switching During Myasthenic Crisis.J Clin Apher202642817013PubTator, text miningPubMed
Rozanolixizumab: A Review in AChR or MuSK Autoantibody-Positive Generalised Myasthenia Gravis.CNS Drugs202642814271PubTator, text miningPubMed
Very Late-Onset Myasthenia Gravis in a Very Elderly Patient: Diagnostic Challenges and Importance of Early Recognition.Geriatrics (Basel)202642776710PubTator, text miningPubMed
Crk/Crk-L-mediated Rapgef1 recruitment couples MuSK signaling to AChR anchoring at the neuromuscular junction.Cell Chem Biol202642772281PubTator, text miningPubMed
Digital assessment in myasthenia gravis: evidence, validation, and a proposed framework for autoimmune heterogeneity, remote monitoring, and clinical endpoints.Front Immunol202642756700PubTator, text miningPubMed
A case report of sequential efgartigimod and rituximab treatment for tSNMG.Front Immunol202642755762PubTator, text miningPubMed
[A differentiated approach to thymectomy in generalized form of myasthenia gravis].Khirurgiia (Mosk)202642735009PubTator, text miningPubMed
TUBA4A Pathogenic Variant Manifesting With Adulthood-Onset Genetic Myasthenic Syndrome, Myopathy, and Infertility.Eur J Neurol202642725680PubTator, text miningPubMed
Motor unit number index (MUNIX) in myasthenia gravis: A cross-sectional pilot sudy.J Electromyogr Kinesiol202642721533PubTator, text miningPubMed
Efgartigimod and Steroid Pulse Therapy as an Early Fast-acting Treatment Strategy for Anti-MUSK Myasthenic Crisis.Intern Med202642716742PubTator, text miningPubMed

1 to 10 of 3,141

See all 3,141 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4593

GET https://conductscience.org/api/genes/v1/4593/patents?page=2