Gene · 4595
MUTYH: mutY DNA glycosylase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MUTYH: mutY DNA glycosylase. Genes, record 4595. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4595
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UIF7 | Adenine DNA glycosylase | 546 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2024123008 A | 2024-09-10 | 7172 | Q9UIF7 | Espacenet |
| US 11504404 B2 | 2022-11-22 | 150 | Q9UIF7 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 53708 | Q9UIF7 | Espacenet |
| US 11401555 B2 | 2022-08-02 | 129 | Q9UIF7 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 156679 | Q9UIF7 | Espacenet |
| JP 2021169490 A | 2021-10-28 | 236 | Q9UIF7 | Espacenet |
| JP 2020521748 A | 2020-07-27 | 5 | Q9UIF7 | Espacenet |
| KR 1020200028897 A | 2020-03-17 | 1 | Q9UIF7 | Espacenet |
| US 10584344 B2 | 2020-03-10 | 150 | Q9UIF7 | Espacenet |
| EP 3585909 A1 | 2020-01-01 | 291 | Q9UIF7 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,658
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MUTYH papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 59 | 2025 |
| R01CA067985 | DNA Damage Repair by MUTYH and MUTYH Variants Associated with Colorectal Cancer | 22 | 2025 |
| U01CA167551 | Colon Cancer Family Registry Cohort | 22 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 21 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 18 | 2025 |
| P30CA015704 | Cancer Center Support Grant | 15 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 14 | 2025 |
| P01CA092584 | Structural Cell Biology of DNA Repair Machines | 13 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 13 | 2025 |
| T32ES007059 | Advanced Training in Environmental Health Sciences | 13 | 2025 |
1 to 10 of 1,658Source NIH's project files
See all 1,658 nih grantsPapers3,741
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| MUTYH Activity Maintains Telomere Stability in Response to Chronic Telomeric 8-Oxoguanine Damage in Cancer Cells. | Biomolecules | 2026 | 42793066 | PubTator, text mining | PubMed |
| Dynamics of mutators of arbitrary dominance in humans. | bioRxiv | 2026 | 42779615 | PubTator, text mining | PubMed |
| MYH gene family associated with high mortality risk in elderly glioma patients with frontal lobe primary site. | Brain Res | 2026 | 42778125 | PubTator, text mining | PubMed |
| From genomic instability to epigenetic regulation: the role of DNA repair gene variants and non-coding RNAs in colorectal carcinogenesis. | Nucleosides Nucleotides Nucleic Acids | 2026 | 42770890 | PubTator, text mining | PubMed |
| Comprehensive Genomic Profiling Reveals the Mutational Spectrum and Clinical Significance of BRCA1/2 and Other Cancer-Susceptibility Genes in Breast Cancer Patients from Southern Tunisia. | Cancers (Basel) | 2026 | 42738331 | PubTator, text mining | PubMed |
| Gastric amphicrine carcinoma in the stomach: an unexpected presentation of MUTYH-associated polyposis. | J Pathol Transl Med | 2026 | 42702572 | PubTator, text mining | PubMed |
| First report of MUTYH-associated polyposis with c.1353_1355del and c.452A>G mutations in Tolima Grande region from Colombia: a case report. | Front Oncol | 2026 | 42676843 | PubTator, text mining | PubMed |
| DNA Damage Recognition by Bacterial and Human Adenine-DNA Glycosylases: Insights from Non-Canonical Substrates. | Biomolecules | 2026 | 42650880 | PubTator, text mining | PubMed |
| The Association of Social and Biological Factors with Clinical Outcomes in Patients with Lung Cancer and DNA Damage Repair Pathway Mutations: A Single-Institution Experience. | Cancers (Basel) | 2026 | 42649919 | PubTator, text mining | PubMed |
| MUTYH activity maintains telomere stability in response to chronic telomeric 8-oxoguanine damage in cancer cells. | bioRxiv | 2026 | 42620046 | PubTator, text mining | PubMed |
1 to 10 of 3,741
See all 3,741 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4595
GET https://conductscience.org/api/genes/v1/4595/patents?page=2