Gene · 4598
MVK: mevalonate kinase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MVK: mevalonate kinase. Genes, record 4598. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4598
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q03426 | Mevalonate kinase | 396 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026515744 A | 2026-05-19 | 219 | Q03426 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 53411 | Q03426 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 707 | Q03426 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 496 | Q03426 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4367 | Q03426 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 496 | Q03426 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 707 | Q03426 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4367 | Q03426 | Espacenet |
| WO 2024214081 A1 | 2024-10-17 | 219 | Q03426 | Espacenet |
| US 11634733 B2 | 2023-04-25 | 9 | Q03426 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants963
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MVK papers | Newest fiscal year |
|---|---|---|---|
| ZIAHG200372 | Genetics, Pathophysiology, and Treatment of Autoinflammatory and Autoimmune Diseases | 11 | 2025 |
| ZIDAR041180 | Clinical Support Services for the NIAMS Intramural Research Program | 9 | 2025 |
| P30DK026743 | UCSF Liver Center | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 4 | 2025 |
| R01DK062370 | Identifying Genes for Type 2 Diabetes: FUSION | 4 | 2025 |
| ZIEAR041176 | Clinical Training in Rheumatology | 4 | 2025 |
| R01AI015614 | Pathogenesis of Fever in Man | 3 | 2025 |
| R01DK113592 | Sterile inflammation and pyroptotic cell death in liver fibrosis | 3 | 2025 |
| ZIAAI001220 | Pathogenesis, and Outcome of Autoinflammatory Diseases, NOMID/CAPS, DIRA, CANDLE, SAVI, NLRC4-MAS, Still's-like Diseases, and other Undifferentiated Autoinflammatory Diseases | 3 | 2025 |
1 to 10 of 963Source NIH's project files
See all 963 nih grantsPapers1,777
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Multi-omics integration reveals tissue-specific biosynthesis of sesquiterpenoids in the medicinal plant Eupatorium lindleyanum. | PLoS One | 2026 | 42821537 | PubTator, text mining | PubMed |
| High-dose short-interval canakinumab therapy for mevalonate kinase deficiency associated with novel MVK variants. | Rheumatology (Oxford) | 2026 | 42814885 | PubTator, text mining | PubMed |
| Postzygotic biallelic inactivation of FDFT1 underlies solitary lesion formation in porokeratosis of Mibelli. | J Dermatol Sci | 2026 | 42716848 | PubTator, text mining | PubMed |
| TiO2-facet-dependent reconstruction of Pt nanoparticles during CO oxidation. | Nat Commun | 2026 | 42706282 | PubTator, text mining | PubMed |
| Floral scent profiling and candidate gene discovery in Hesperis oreophila. | Front Plant Sci | 2026 | 42609380 | PubTator, text mining | PubMed |
| Novel compound heterozygous MVK variants cause early-onset mevalonic aciduria in a Chinese infant. | Front Pediatr | 2026 | 42529070 | PubTator, text mining | PubMed |
| Plasma Proteomics Identifies Proteins and Pathways Associated with Cataract: A Prospective Cohort Study. | Ophthalmol Sci | 2026 | 42518793 | PubTator, text mining | PubMed |
| "Golden flower" development of Aspergillus cristatus determined the sensory characteristic and aroma compounds of Fu brick tea. | Int J Food Microbiol | 2026 | 42480482 | PubTator, text mining | PubMed |
| Multiplex RT-PCR-Based Sequencing Assay to Detect Kidney Cancer-Specific Splice Variants in Tumor Tissues and Plasma Cell-Free RNAs. | Mol Diagn Ther | 2026 | 42410176 | PubTator, text mining | PubMed |
| Genotype-phenotype correlations in autoimmune and autoinflammatory diseases: An NGS-based immunogenetic cohort study. | Immunogenetics | 2026 | 42406132 | PubTator, text mining | PubMed |
1 to 10 of 1,777
See all 1,777 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4598
GET https://conductscience.org/api/genes/v1/4598/patents?page=2