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Gene · 4610

MYCL: MYCL proto-oncogene, bHLH transcription factor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MYCL: MYCL proto-oncogene, bHLH transcription factor. Genes, record 4610. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4610

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Gene

Symbol
MYCL
HGNC
Name
MYCL proto-oncogene, bHLH transcription factor
HGNC
NCBI Gene ID
4610
NCBI Gene
HGNC ID
HGNC:7555
HGNC
Ensembl
ENSG00000116990
NCBI Gene
Aliases
L-Myc, LMYC, MYCL1, bHLHe38
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P12524Protein L-Myc3640Ensembl, GeneID, HGNC

Source UniProt

Patents58

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026091847 A2026-06-0411P12524Espacenet
JP 2026086827 A2026-05-268P12524Espacenet
EP 4711449 A12026-03-184P12524Espacenet
JP 2025147176 A2025-10-0615325P12524Espacenet
JP 2025530805 A2025-09-1743P12524Espacenet
KR 1020250068664 A2025-05-1643P12524Espacenet
EP 4553154 A12025-05-1421P12524Espacenet
JP 2025065482 A2025-04-174P12524Espacenet
JP 2025507265 A2025-03-188P12524Espacenet
JP 2025032204 A2025-03-1131936P12524Espacenet

1 to 10 of 58

See all 58 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,825

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMYCL papersNewest fiscal year
P30CA008748Cancer Center Support Grant282025
P30CA016672Cancer Center Support Grant282025
P30CA033572Cancer Center Support Grant152025
U24CA213274Coordinating center for the NCI small cell lung cancer research consortium152025
P30CA015704Cancer Center Support Grant132025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant92025
P30CA068485Cancer Center Support Grant82025
P01CA120964Molecular Pathogenesis of the Hamartoma Syndromes72025
P30CA016056Roswell Park Cancer Center Support Grant62025
P30CA021765Cancer Center Support Grant (CCSG)62025

1 to 10 of 1,825Source NIH's project files

See all 1,825 nih grants

Papers2,575

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Genomic and Transcriptomic Features of Relapsed SCLC.J Thorac Oncol202642749049PubTator, text miningPubMed
Targeting MYC-Driven Cancers: From Oncogenic Addiction to Therapeutic Vulnerability.BioDrugs202642684666PubTator, text miningPubMed
CMA-associated cellular state remodeling defines prognostic heterogeneity and identifies ARRDC3 as a protective functional gene in small cell lung cancer.Front Cell Dev Biol202642564958PubTator, text miningPubMed
Inhibition of the ATR-CHK1 signaling pathway sensitizes MCPyV-positive Merkel cell carcinoma to gemcitabine.BMC Cancer202642458330PubTator, text miningPubMed
The MYC network: Hub of malignancy and blueprint for intervention.Biochim Biophys Acta Rev Cancer202642385913PubTator, text miningPubMed
Targeted degradation of MDM2 overcomes feedback regulation of p53 signaling in Merkel cell carcinoma models.J Clin Invest202642383359PubTator, text miningPubMed
The Genomic Landscape of MYC-, MYCL-, and MYCN-Amplified Solid Tumors.Clin Cancer Res202642340371PubTator, text miningPubMed
Structure and function of the L-MYC N-terminus impacts strategies to inhibit the MYC family of oncoproteins.Biochem J202642030451PubTator, text miningPubMed
A MYC family switch: L-MYC drives and maintains neuroendocrine lineage programs in prostate cancer.Neoplasia202642001796PubTator, text miningPubMed
Establishment of an induced pluripotent stem cell line BTHBIOi003-A from a Leber's congenital amaurosis patient.Stem Cell Res202642000543PubTator, text miningPubMed

1 to 10 of 2,575

See all 2,575 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4610

GET https://conductscience.org/api/genes/v1/4610/patents?page=2