Gene · 4616
GADD45B: growth arrest and DNA damage inducible beta
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. GADD45B: growth arrest and DNA damage inducible beta. Genes, record 4616. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4616
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O75293 | Growth arrest and DNA damage-inducible protein GADD45 beta | 160 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents44
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4805378 A1 | 2026-09-16 | 688 | O75293 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 271 | O75293 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4305 | O75293 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 271 | O75293 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4305 | O75293 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 6380 | O75293 | Espacenet |
| US 11708396 B2 | 2023-07-25 | 2221 | O75293 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 36377 | O75293 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 139348 | O75293 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 4298 | O75293 | Espacenet |
1 to 10 of 44
See all 44 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,506
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | GADD45B papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 10 | 2025 |
| P50AA022538 | Center for Alcohol Research in Epigenetics | 8 | 2025 |
| P30CA016087 | Cancer Center Support Grant | 5 | 2025 |
| ZICES102445 | Gene Expression and Microarrays | 5 | 2025 |
| P01CA108671 | Myeloproliferative Neoplasms-Research Consortium | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 4 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| P42ES004911 | Environmental, Microbial and Mammalian Biomolecular Responses to AhR Ligands | 4 | 2025 |
1 to 10 of 1,506Source NIH's project files
See all 1,506 nih grantsPapers2,130
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| 6PPD-Quinone Promotes Metabolic Dysfunction-Associated Steatotic Liver Disease through Immune-Inflammatory Disruption. | Environ Sci Technol | 2026 | 42814397 | PubTator, text mining | PubMed |
| Deciphering the impact of genetic variants on vulnerability to Opioid Use Disorder. | Front Cell Neurosci | 2026 | 42787119 | PubTator, text mining | PubMed |
| A refined MASH-HCC model identifies macrophage Gadd45b as a key orchestrator of inflammation-driven neoplastic progression. | Exp Mol Med | 2026 | 42749878 | PubTator, text mining | PubMed |
| Gadd45β is critical for regulation of type I interferon signaling by facilitating G3BP-mediated stress granule formation. | Cell Rep | 2026 | 42731031 | PubTator, text mining | PubMed |
| Fermentation with aspergillus costiformis enhances the anti-migratory activity of Aquilaria sinensis leaves with possible involvement of MAPK-related pathways. | Food Res Int | 2026 | 42632702 | PubTator, text mining | PubMed |
| Pathophysiological and translational implications of the dysregulation of molecular machineries controlling RNA metabolism in thyrotropinomas. | iScience | 2026 | 42602702 | PubTator, text mining | PubMed |
| Apoptosis protein markers in comorbid type 2 diabetes mellitus and depression; relationships with cognitive performance, incident dementia, and white matter hyperintensities. | J Affect Disord | 2026 | 42556583 | PubTator, text mining | PubMed |
| Hepatic responses as potential biomarkers of idiosyncratic drug reaction risk. | Toxicol Sci | 2026 | 42523165 | PubTator, text mining | PubMed |
| Engineering Stable Lentiviral Vector Producer Cells Improves LVV Production. | Biotechnol Bioeng | 2026 | 42478279 | PubTator, text mining | PubMed |
| Identification of GADD45B, HMGB3, LMNB2, and MFAP5 as lactylation-related prognostic markers for survival prediction in esophageal cancer. | Transl Cancer Res | 2026 | 42445420 | PubTator, text mining | PubMed |
1 to 10 of 2,130
See all 2,130 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4616
GET https://conductscience.org/api/genes/v1/4616/patents?page=2