Gene · 4620
MYH2: myosin heavy chain 2
12 sourcesgene-search-2026-11-11-0.2.0
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ConductScience Library. MYH2: myosin heavy chain 2. Genes, record 4620. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4620
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Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q9UKX2 | Myosin-2 | 1,941 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents38
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 54712 | Q9UKX2 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 54713 | Q9UKX2 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1156 | Q9UKX2 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 819 | Q9UKX2 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 819 | Q9UKX2 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1156 | Q9UKX2 | Espacenet |
| JP 2023516705 A | 2023-04-20 | 89 | Q9UKX2 | Espacenet |
| JP 2022141755 A | 2022-09-29 | 633 | Q9UKX2 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 54524 | Q9UKX2 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 54525 | Q9UKX2 | Espacenet |
1 to 10 of 38
See all 38 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants820
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MYH2 papers | Newest fiscal year |
|---|---|---|---|
| R01GM029090 | Myosin Gene Diversity and Function | 14 | 2025 |
| ZIAHL001786 | Regulation Of Smooth and Nonmuscle Myosin | 9 | 2025 |
| ZIAHL004232 | Expression Studies of Other Unconventional Myosins | 8 | 2025 |
| R35GM138183 | MECHANISMS OF CONTRACTILE NETWORK ASSEMBLY | 5 | 2025 |
| R01AG044615 | Respiratory Control in Old Age | 4 | 2025 |
| ZIAAG000996 | GESTALT-Genetic and Epigenetic Signatures of Translational Aging Laboratory Testing | 4 | 2025 |
| P30AG024827 | Pittsburgh Older Americans Independence Center | 3 | 2025 |
| R01DK095811 | Molecular basis of brush border assembly | 3 | 2025 |
| T32HD043730 | Fuller T32 renewal | 3 | 2025 |
| ZIADC000048 | Functional Studies of "Deafness Genes" Essential for Hearing | 3 | 2025 |
1 to 10 of 820Source NIH's project files
See all 820 nih grantsPapers1,369
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Exploratory transcriptomic analysis of low-grade oral epithelial dysplasia and oral squamous cell carcinoma in Chilean patients. | Mol Biol Rep | 2026 | 42525276 | PubTator, text mining | PubMed |
| A Novel Homozygous MYH2 Variant Causing Early-Onset External Ophthalmoplegia and Proximal Myopathy in a Consanguineous Family. | Cureus | 2026 | 42491855 | PubTator, text mining | PubMed |
| Systematic reanalysis of next-generation sequencing data in 101 neuromuscular disorder families enhances diagnostic yield, reveals intronic variants, and identifies a novel disease gene. | J Neurol | 2026 | 42474733 | PubTator, text mining | PubMed |
| Substrate stiffness regulates HIF-1α signalling via β1-integrin/myosin-2/NF-κB axis. | J Transl Med | 2026 | 42421092 | PubTator, text mining | PubMed |
| MYH2 as a Potential Modifier of Clinical Severity in Facioscapulohumeral Muscular Dystrophy. | J Mol Neurosci | 2026 | 42390820 | PubTator, text mining | PubMed |
| The other half of the sprinting coin: the neuromuscular profile of a 91-yr-old female world record sprinter. | J Appl Physiol (1985) | 2026 | 42090218 | PubTator, text mining | PubMed |
| Whole-exome sequencing unveils novel potential gene mutations involved in primary renal small cell carcinoma. | Oncol Lett | 2026 | 41969585 | PubTator, text mining | PubMed |
| The Conjugated Bile Acids Profile Suggests a Novel Liver-Muscle Axis Associated With Sarcopenia in Chronic Liver Disease. | Liver Int | 2026 | 41902587 | PubTator, text mining | PubMed |
| A new MYH2 variant in an Italian patient expanding the clinical spectrum of MYH2-related myopathy. | BMC Neurol | 2026 | 41851877 | PubTator, text mining | PubMed |
| Quercetin attenuates deoxynivalenol-induced muscle developmental disorders in broilers by modulating the PI3K/Akt/mTOR pathway and reducing apoptosis. | Poult Sci | 2026 | 41850073 | PubTator, text mining | PubMed |
1 to 10 of 1,369
See all 1,369 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
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