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Gene · 4624

MYH6: myosin heavy chain 6

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. MYH6: myosin heavy chain 6. Genes, record 4624. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/4624

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
MYH6
HGNC
Name
myosin heavy chain 6
HGNC
NCBI Gene ID
4624
NCBI Gene
HGNC ID
HGNC:7576
HGNC
Ensembl
ENSG00000197616
NCBI Gene
Aliases
ASD3, CMD1EE, CMH14, MYHC, MYHCA, SSS3, alpha-MHC
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P13533Myosin-61,9390Ensembl, GeneID, HGNC

Source UniProt

Patents46

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1454719P13533Espacenet
JP 2026004568 A2026-01-1454720P13533Espacenet
EP 4640849 A22025-10-291933P13533Espacenet
EP 4641201 A22025-10-2912857P13533Espacenet
JP 2025519096 A2025-06-241933P13533Espacenet
JP 2025517969 A2025-06-1212857P13533Espacenet
JP 2025508740 A2025-04-10119P13533Espacenet
JP 2025032204 A2025-03-1131955P13533Espacenet
JP 2025032204 A2025-03-1131956P13533Espacenet
EP 4479433 A22024-12-25119P13533Espacenet

1 to 10 of 46

See all 46 patents

Drugs3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
DANICAMTIVCHEMBL4594304Cardiac myosin activatorACTIVATORChEMBL
MAVACAMTENCHEMBL4297517Cardiac myosin inhibitorINHIBITORChEMBL
OMECAMTIV MECARBILCHEMBL1800955Cardiac myosin activatorACTIVATORChEMBL

Trials45

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants3,211

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
R01GM029090Myosin Gene Diversity and Function242025
R01HL113006Human Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling142025
R01HL092577IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL112025
R01HL130020Elucidating Mechanism of Cardiac Fibrosis with Cell Village of Pooled Human iPSCs112025
R01HL131017Myocardial remuscularization by cardiac patch delivery of epicardial FSTL1 and CCND2 overexpressing cardiomyocytes102025
T32HL007208Integrated, Multidisciplinary Training in Cardiovascular Research102025
R01HL076485Engineering Vascularized Cardiac Muscle92025
T32HL007572Research Methods in Pediatric Cardiovascular Disease82025
T32HL007828Cardiovascular Research Training Program82025
P30DK063491Diabetes Research Center (DRC)72025

1 to 10 of 3,211Source NIH's project files

See all 3,211 nih grants

Papers4,586

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42812170PubTator, text miningPubMed
42780728PubTator, text miningPubMed
42760933PubTator, text miningPubMed
42724214PubTator, text miningPubMed
42692018PubTator, text miningPubMed
42680482PubTator, text miningPubMed
42661636PubTator, text miningPubMed
42656803PubTator, text miningPubMed
42635923PubTator, text miningPubMed
42630156PubTator, text miningPubMed

1 to 10 of 4,586

See all 4,586 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4624

GET https://conductscience.org/api/genes/v1/4624/patents?page=2