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MYH7: myosin heavy chain 7

1 protein, 26 patents, 3 drugs, 45 trials, 2,598 NIH grants and 4,899 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMYH7HGNC
Namemyosin heavy chain 7HGNC
NCBI Gene ID4625NCBI Gene
HGNC IDHGNC:7577HGNC
EnsemblENSG00000092054NCBI Gene
AliasesCMD1S, CMH1, CMYO7A, CMYO7B, CMYP7A, CMYP7B, MPD1, MYHCB, SPMD, SPMMNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P12883Myosin-71,93546Ensembl, GeneID, HGNCUniProt

Patents 26

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1454721P12883Espacenet
EP 4641201 A22025-10-297076P12883Espacenet
JP 2025517969 A2025-06-127076P12883Espacenet
JP 2025508740 A2025-04-10251P12883Espacenet
EP 4479433 A22024-12-25251P12883Espacenet
JP 2024529294 A2024-08-0697P12883Espacenet
EP 4363589 A12024-05-0897P12883Espacenet
KR 1020240029030 A2024-03-0597P12883Espacenet
JP 2023106701 A2023-08-0239P12883Espacenet
JP 2022141755 A2022-09-29517P12883Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
DANICAMTIVCHEMBL4594304Cardiac myosin activatorACTIVATORChEMBL
MAVACAMTENCHEMBL4297517Cardiac myosin inhibitorINHIBITORChEMBL
OMECAMTIV MECARBILCHEMBL1800955Cardiac myosin activatorACTIVATORChEMBL

Trials 45

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07557498MAVACAMTENClinicalTrials.gov
NCT07541833MAVACAMTENClinicalTrials.gov
NCT07529938MAVACAMTENClinicalTrials.gov
NCT07383025MAVACAMTENClinicalTrials.gov
NCT07361289MAVACAMTENClinicalTrials.gov
NCT07210723DANICAMTIVPHASE2/PHASE3ClinicalTrials.gov
NCT07168655MAVACAMTENClinicalTrials.gov
NCT07150299MAVACAMTENClinicalTrials.gov
NCT07120776MAVACAMTENClinicalTrials.gov
NCT07107373MAVACAMTENClinicalTrials.gov

NIH grants 2598

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01GM029090Myosin Gene Diversity and Function242,025NIH's project files
R01HL113006Human Induced Pluripotent Stem Cells for Cardiovascular Disease Modeling162,025NIH's project files
R01HL130020Elucidating Mechanism of Cardiac Fibrosis with Cell Village of Pooled Human iPSCs152,025NIH's project files
R01HL105826Fast myosin binding protein-C and cardiac contractility in heart failure132,025NIH's project files
T32HL094274Training in Myocardial Biology at Stanford132,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award122,025NIH's project files
ZIANS003129Molecular and Clinical Manifestations of Matrix and Aggregate Myopathies112,025NIH's project files
R01HL075619Integrative Approach to Divergent Remodeling in Thin Filament Cardiomyopathies102,025NIH's project files
R01HL092577IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL92,025NIH's project files
R01HL132401Mechanisms and Therapeutic Targeting of DNA Damage in Dilated Cardiomyopathy Caused by LMNA Mutations82,025NIH's project files

Papers 4899

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42795368PubTator, text miningPubMed
42794001PubTator, text miningPubMed
42779549PubTator, text miningPubMed
42772561PubTator, text miningPubMed
42761940PubTator, text miningPubMed
42755847PubTator, text miningPubMed
42746568PubTator, text miningPubMed
42698999PubTator, text miningPubMed
42697879PubTator, text miningPubMed
42692018PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license