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Gene · 463

ZFHX3: zinc finger homeobox 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ZFHX3: zinc finger homeobox 3. Genes, record 463. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/463

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Gene

Symbol
ZFHX3
HGNC
Name
zinc finger homeobox 3
HGNC
NCBI Gene ID
463
NCBI Gene
HGNC ID
HGNC:777
HGNC
Ensembl
ENSG00000140836
NCBI Gene
Aliases
ATBF1, ATBT, ATFB8, C16orf47, EIG20, FLJ26184, SCA4, ZFH-3, ZNF927
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q15911Zinc finger homeobox protein 33,7033Ensembl, GeneID, HGNC

Source UniProt

Patents25

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1470232Q15911Espacenet
EP 4640849 A22025-10-29322Q15911Espacenet
EP 4641201 A22025-10-292244Q15911Espacenet
JP 2025147176 A2025-10-0615916Q15911Espacenet
JP 2025519096 A2025-06-24322Q15911Espacenet
JP 2025517969 A2025-06-122244Q15911Espacenet
JP 2025028160 A2025-02-2815916Q15911Espacenet
KR 1020250010750 A2025-01-2115916Q15911Espacenet
JP 2024530931 A2024-08-2714Q15911Espacenet
JP 2024109657 A2024-08-1415755Q15911Espacenet

1 to 10 of 25

See all 25 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,248

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleZFHX3 papersNewest fiscal year
R01HL092577IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL262025
P30CA008748Cancer Center Support Grant182025
P30DK063491Diabetes Research Center (DRC)102025
R01NS017950Precursors of Stroke Incidence and Prognosis102025
P30CA016672Cancer Center Support Grant72025
R01HL086694From GWAS loci to blood pressure genes, variants & mechanisms - Renewal62025
ZIAHL006001Framingham Project/Levy62025
UL1TR001863Yale Clinical and Translational Science Award52025
UL1TR001881UCLA Clinical and Translational Science Institute52025
ZIAAG007270ALZHEIMERS RESEARCH PROJECT: Genetic Markers of Brain Aging52025

1 to 10 of 1,248Source NIH's project files

See all 1,248 nih grants

Papers1,316

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Large-scale genetic profiling of hereditary ataxias in China: implications for a stepwise molecular diagnostic strategy.Transl Neurodegener202642806408PubTator, text miningPubMed
Genomic and transcriptomic correlates of deep prostate-specific antigen response in patients with metastatic androgen pathway modulation-sensitive prostate cancer.Oncologist202642752828PubTator, text miningPubMed
Characterising the motif composition and allele length distribution of ZFHX3 GGC repeat expansions in amyotrophic lateral sclerosis.J Hum Genet202642736322PubTator, text miningPubMed
Recurrent mechanisms of biallelic epigenetic inactivation reveal new putative tumour suppressor genes in prostate cancer.Nat Commun202642716948PubTator, text miningPubMed
Functional convergence of regulatory regions provides vital insights into mammalian gliding adaptation.Sci China Life Sci202642714797PubTator, text miningPubMed
Serum Peptidomic Analysis in a Comparative Study of the Efficacy of Benjakul Remedy Versus Loratadine in Allergic Rhinitis Patients.Int J Mol Sci202642653391PubTator, text miningPubMed
How does genetic susceptibility impact the effectiveness of AF ablation?Hellenic J Cardiol202642648599PubTator, text miningPubMed
Cell villages and Dirichlet modeling map human cell fitness genetics.Am J Hum Genet202642546692PubTator, text miningPubMed
Integrative multi-omics reveals a fibroblast-centered, ZFHX3-prioritized regulatory framework linking sick sinus syndrome and atrial fibrillation.Cell Signal202642543078PubTator, text miningPubMed
Shared Genetics of Kidney Function Traits and Bladder Cancer: A Genome-Wide Cross-Trait Analysis.Cancer Med202642470241PubTator, text miningPubMed

1 to 10 of 1,316

See all 1,316 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/463

GET https://conductscience.org/api/genes/v1/463/patents?page=2