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Gene · 4635

MYL4: myosin light chain 4

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MYL4: myosin light chain 4. Genes, record 4635. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4635

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Gene

Symbol
MYL4
HGNC
Name
myosin light chain 4
HGNC
NCBI Gene ID
4635
NCBI Gene
HGNC ID
HGNC:7585
HGNC
Ensembl
ENSG00000198336
NCBI Gene
Aliases
ALC1, AMLC, GT1, PRO1957
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P12829Myosin light chain 41970Ensembl, GeneID, HGNC

Source UniProt

Patents21

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1454735P12829Espacenet
JP 2026004568 A2026-01-1454736P12829Espacenet
US 11446398 B22022-09-2054565P12829Espacenet
US 11446398 B22022-09-2054566P12829Espacenet
US 11446398 B22022-09-2054573P12829Espacenet
JP 2022524081 A2022-04-27157536P12829Espacenet
JP 2022524081 A2022-04-27157537P12829Espacenet
JP 2022524081 A2022-04-27157544P12829Espacenet
US 11078247 B22021-08-037171P12829Espacenet
JP 2019054813 A2019-04-11235170P12829Espacenet

1 to 10 of 21

See all 21 patents

Drugs3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
DANICAMTIVCHEMBL4594304Cardiac myosin activatorACTIVATORChEMBL
MAVACAMTENCHEMBL4297517Cardiac myosin inhibitorINHIBITORChEMBL
OMECAMTIV MECARBILCHEMBL1800955Cardiac myosin activatorACTIVATORChEMBL

Trials45

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants458

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMYL4 papersNewest fiscal year
R01HL092577IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVAL42025
K08HL159346Deep learning to enable the genetic analysis of aorta22025
P30CA008748Cancer Center Support Grant22025
P30DK063491Diabetes Research Center (DRC)22025
R01HD101130Establishing an In Vitro Embryotoxicity Risk Classification System Based on Human Cardiac Organoid Model22025
R01HL057181Cardiogenesis: Molecular Mechanisms22025
R01HL076485Engineering Vascularized Cardiac Muscle22025
R01HL141278Alternative Protein Isoforms in Ventricular Remodeling22025
T32HL007604Training Grant in Cardiovascular Research22025
K08HL153937Population Assessments of Aggregate Genetic Risk for Dilated Cardiomyopathy12025

1 to 10 of 458Source NIH's project files

See all 458 nih grants

Papers540

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
The Genetics of Atrial Fibrillation: From Molecular Mechanisms to Precision Medicine.Cureus202642371450PubTator, text miningPubMed
Multi-omics investigation of perineural invasion in head and neck squamous cell carcinoma: neuroimmune mechanisms and clinical implications.Front Immunol202642206060PubTator, text miningPubMed
Genome-wide association study of myopia progression in Chinese adolescents and application of polygenic risk score prediction.Front Chem202642094695PubTator, text miningPubMed
Transcriptomic Profiling Identifies a Distinct Molecular Signature in OSMF-Derived Oral Squamous Cell Carcinoma.Life (Basel)202641900972PubTator, text miningPubMed
Multimodal Spatial Transcriptomics Reveals the Developing Human Liver Niche at Single-Cell Resolution.Gastro Hep Adv202641798887PubTator, text miningPubMed
Single-Cell Multi-Omics Profiling of Human Septal Myectomy Tissue: Toward Precision Medicine in Obstructive Hypertrophic Cardiomyopathy.J Pers Med202641745380PubTator, text miningPubMed
Chamber-specific transcriptomic insight into cardiac development using guinea pig and human heart tissue.Physiol Genomics202641196187PubTator, text miningPubMed
Shared gene functions in autoimmune diseases identified via integrated bioinformatics analysis.Cell Mol Biol (Noisy-le-grand)202541351370PubTator, text miningPubMed
Linezolid impair proplatelet formation by reducing mitochondrial energy metabolism in MEG-01 cells.Thromb Res202541005026PubTator, text miningPubMed
Size-Modulated Mesoderm-Endoderm Divergence and Myocardial Cavitation in Micropatterned Cardioids.bioRxiv202541000917PubTator, text miningPubMed

1 to 10 of 540

See all 540 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4635

GET https://conductscience.org/api/genes/v1/4635/patents?page=2