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Gene · 4680

CEACAM6: CEA cell adhesion molecule 6

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. CEACAM6: CEA cell adhesion molecule 6. Genes, record 4680. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4680

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Gene

Symbol
CEACAM6
HGNC
Name
CEA cell adhesion molecule 6
HGNC
NCBI Gene ID
4680
NCBI Gene
HGNC ID
HGNC:1818
HGNC
Ensembl
ENSG00000086548
NCBI Gene
Aliases
CD66c, CEAL, NCA, NCA-50/90
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P40199Cell adhesion molecule CEACAM63446Ensembl, GeneID, HGNC

Source UniProt

Patents102

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026167227 A12026-08-131P40199Espacenet
WO 2025257715 A12025-12-1827P40199Espacenet
JP 2025539841 A2025-12-0954P40199Espacenet
EP 4641201 A22025-10-29169P40199Espacenet
JP 2025517969 A2025-06-12169P40199Espacenet
EP 4548937 A12025-05-071P40199Espacenet
JP 2025062604 A2025-04-1411955P40199Espacenet
US 12121590 B22024-10-2280P40199Espacenet
US 12076365 B22024-09-034P40199Espacenet
JP 2024522076 A2024-06-1187P40199Espacenet

1 to 10 of 102

See all 102 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants980

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleCEACAM6 papersNewest fiscal year
P30CA016672Cancer Center Support Grant132025
P30CA008748Cancer Center Support Grant82025
P30DK034987Center for Gastrointestinal Biology and Disease72025
P30CA016056Roswell Park Cancer Center Support Grant42025
P30CA016086Cancer Center Support Grant42025
P30CA076292Moffitt Cancer Center Support Grant42025
P40OD010995National Gnotobiotic Resource Center42025
R01DK051362Regulation of Mucosal Lymphocytes42025
R01DK091281A Novel Role for PTPN2 in Intestinal Epithelial Barrier Regulation42025
R35HL145235Airway epithelial cell gene regulation: new mechanisms and therapeutic strategies42025

1 to 10 of 980Source NIH's project files

See all 980 nih grants

Papers1,711

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrative transcriptomic analysis of peripheral blood identifies NETosis-associated programs and a stratified adaptive immune suppression pattern in severe acute pancreatitis.PLoS One202642789536PubTator, text miningPubMed
Growth Differentiation Factor 15 as a Cerebrospinal Fluid Biomarker for the Diagnosis and Prognosis of Leptomeningeal Metastasis.Ann Neurol202642770667PubTator, text miningPubMed
Patient-Derived Organoid and Single-Cell Multiomics Reveal Evolution Driven by CEACAM6/KRT19-Mediated Heterogeneity.FASEB J202642622615PubTator, text miningPubMed
Single-Cell Profiling Identifies the SPDEF/GAS5 Axis as a Potential Driver of Tamoxifen Resistance in Estrogen Receptor-Positive Breast Cancer.Cureus202642528776PubTator, text miningPubMed
Protein glycosylation profiling in lung adenocarcinoma and precursor lesions: analysis of FFPE tissue sections.Anal Bioanal Chem202642509285PubTator, text miningPubMed
Clinical and molecular correlates of digitally quantified anthracosis in lung tissue slides: utility of an automated quantitative workflow.J Pathol Clin Res202642473194PubTator, text miningPubMed
Corrigendum to: "A heavy-chain antibody-drug conjugate targeting glycosylated CEACAM6 inhibits brain metastatic tumor growth" [Cancer Lett. 648, (2026) 218463].Cancer Lett202642469116PubTator, text miningPubMed
Normalized internalization predicts potency of carcinoembryonic antigen-related cell adhesion molecule 6-targeting antibody-drug conjugates.J Control Release202642309467PubTator, text miningPubMed
Targeting Circulating Tumor Cells in Pancreatic Ductal Adenocarcinoma: Rationale, Current Evidence, and a CEACAM6 CAR-T Strategy.Cancers (Basel)202642279434PubTator, text miningPubMed
SLC22A4 as a candidate regulator linking immunity and ferroptosis in septic shock.Mol Immunol202642275906PubTator, text miningPubMed

1 to 10 of 1,711

See all 1,711 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4680

GET https://conductscience.org/api/genes/v1/4680/patents?page=2