Gene · 4688
NCF2: neutrophil cytosolic factor 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NCF2: neutrophil cytosolic factor 2. Genes, record 4688. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4688
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P19878 | Neutrophil cytosol factor 2 | 526 | 7 | Ensembl, GeneID, HGNC |
Source UniProt
Patents35
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 55612 | P19878 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 55613 | P19878 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 1246 | P19878 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 8426 | P19878 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 5398 | P19878 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 1246 | P19878 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 8426 | P19878 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 5398 | P19878 | Espacenet |
| US 11860162 B2 | 2024-01-02 | 1219 | P19878 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 56733 | P19878 | Espacenet |
1 to 10 of 35
See all 35 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,090
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NCF2 papers | Newest fiscal year |
|---|---|---|---|
| ZIAAI000646 | Transgenic Animal Models Of Human Immune Defects | 23 | 2025 |
| ZIAAI000644 | Gene Therapy and Hematopoietic Stem Cell Research to Treat Inherited Primary Immune Deficiencies | 15 | 2025 |
| ZIAAI000645 | Development and Clinical Application of Gene and Cell therapies for Patients with Immune Deficiencies | 15 | 2025 |
| R01AI024717 | Genetic Linkage in Lupus | 8 | 2025 |
| U54GM104938 | Oklahoma Shared Clinical and Translational Resources | 7 | 2025 |
| ZIABC010677 | NADPH Oxidases as Novel Targets for Cancer Therapy | 7 | 2025 |
| P30CA082709 | Indiana University Melvin and Bren Simon Comprehensive Cancer Center Support Grant | 5 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 5 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 5 | 2025 |
| P30DK034989 | Yale Liver Center | 5 | 2025 |
1 to 10 of 2,090Source NIH's project files
See all 2,090 nih grantsPapers3,069
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Human inborn errors of the phagocyte respiratory burst: Chronic granulomatous disease and beyond. | J Hum Immun | 2026 | 42758005 | PubTator, text mining | PubMed |
| Integration of transcriptomics and machine learning to explore inflammatory characteristics and key oxidative stress-related molecules in nasal polyps. | Front Immunol | 2026 | 42718792 | PubTator, text mining | PubMed |
| Design, synthesis, and pharmacological evaluation of terrein derivatives targeting hepatocellular carcinoma. | Eur J Med Chem | 2026 | 42679701 | PubTator, text mining | PubMed |
| Mepolizumab Modifies Blood Eosinophil Proteome and Transcriptome in Severe Eosinophilic Asthma. | Allergy | 2026 | 42655930 | PubTator, text mining | PubMed |
| Endoplasmic Reticulum Stress-Related Immune Signature in Atrial Fibrillation: Machine Learning and Single-Cell Transcriptomics. | J Vis Exp | 2026 | 42611890 | PubTator, text mining | PubMed |
| Apoptosis-related genes bridge inflammatory bowel disease and osteoporosis: A bioinformatic analysis. | PLoS One | 2026 | 42585215 | PubTator, text mining | PubMed |
| Beneficial effects of antioxidants on neutrophil extracellular trap formation in atherosclerosis. | Arch Med Sci | 2026 | 42540628 | PubTator, text mining | PubMed |
| Integrative Multiomics and Single-cell Profiling Identify Cell-type-resolved Inflammatory Drivers in Symptomatic Irreversible Pulpitis. | J Endod | 2026 | 42486295 | PubTator, text mining | PubMed |
| Expression Profile and Clinical Significance of Ferroptosis-Related Genes in Peripheral Blood Mononuclear Cells of Patients with Systemic Sclerosis. | Curr Rheumatol Rev | 2026 | 42459084 | PubTator, text mining | PubMed |
| Hydrogen sulfide modulates gene networks in hypoxia/reoxygenation-stressed trophoblasts: insights from transcriptome profiling. | Front Bioinform | 2026 | 42382641 | PubTator, text mining | PubMed |
1 to 10 of 3,069
See all 3,069 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4688
GET https://conductscience.org/api/genes/v1/4688/patents?page=2