Gene · 4689
NCF4: neutrophil cytosolic factor 4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NCF4: neutrophil cytosolic factor 4. Genes, record 4689. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4689
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q15080 | Neutrophil cytosol factor 4 | 339 | 6 | Ensembl, GeneID, HGNC |
Source UniProt
Patents18
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 55619 | Q15080 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4441 | Q15080 | Espacenet |
| EP 4504259 A1 | 2025-02-12 | 2 | Q15080 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4441 | Q15080 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 56739 | Q15080 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 159710 | Q15080 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 7303 | Q15080 | Espacenet |
| WO 2020043864 A1 | 2020-03-05 | 1578 | Q15080 | Espacenet |
| WO 2019161400 A1 | 2019-08-22 | 13 | Q15080 | Espacenet |
| WO 2019161400 A1 | 2019-08-22 | 25 | Q15080 | Espacenet |
1 to 10 of 18
See all 18 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,541
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NCF4 papers | Newest fiscal year |
|---|---|---|---|
| ZIAAI000646 | Transgenic Animal Models Of Human Immune Defects | 20 | 2025 |
| ZIAAI000644 | Gene Therapy and Hematopoietic Stem Cell Research to Treat Inherited Primary Immune Deficiencies | 14 | 2025 |
| ZIAAI000645 | Development and Clinical Application of Gene and Cell therapies for Patients with Immune Deficiencies | 13 | 2025 |
| P30DK034854 | Integrated Epithelial and Muscosal Biology | 6 | 2025 |
| P30DK043351 | Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital | 6 | 2025 |
| U01DK062413 | Determining genomic and host-environment contributions to IBD phenotypes | 6 | 2025 |
| U01DK062422 | Mount Sinai NYC Genetics Research Center: Multi-omic integration across data-types, cell niches and populations | 5 | 2025 |
| ZIAAI000989 | Development and conduct of allogeneic stem cell transplant and autologous stem cell gene therapy for inherited immune deficiencies | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA082709 | Indiana University Melvin and Bren Simon Comprehensive Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 1,541Source NIH's project files
See all 1,541 nih grantsPapers1,992
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Genetically engineered porcine liver: a new era in transplantation. | Int J Surg | 2026 | 42808109 | PubTator, text mining | PubMed |
| Human inborn errors of the phagocyte respiratory burst: Chronic granulomatous disease and beyond. | J Hum Immun | 2026 | 42758005 | PubTator, text mining | PubMed |
| Multi-omics analysis identifies macrophage immunometabolic signatures in ulcerative colitis. | Front Cell Infect Microbiol | 2026 | 42755516 | PubTator, text mining | PubMed |
| Integration of transcriptomics and machine learning to explore inflammatory characteristics and key oxidative stress-related molecules in nasal polyps. | Front Immunol | 2026 | 42718792 | PubTator, text mining | PubMed |
| Common Molecular Mechanisms and Candidate Drug Targets in Type 2 Diabetes Mellitus and Atherosclerotic Cardiovascular Disease. | J Vis Exp | 2026 | 42612061 | PubTator, text mining | PubMed |
| Pharmacogenomic variation and chemotherapy-related toxicity profiles in pediatric patients with cancer in Tanzania: a cross-sectional study. | Front Pharmacol | 2026 | 42548792 | PubTator, text mining | PubMed |
| Oxidative DNA Damage as an Integrative Marker of Redox Dysfunction Associated with Doxorubicin-Induced Cardiotoxicity in Pediatric Leukemia. | Curr Issues Mol Biol | 2026 | 42353582 | PubTator, text mining | PubMed |
| Chronic granulomatous disease: Clinical, microbial, and genetic findings in 39 Colombian patients. | J Hum Immun | 2026 | 42180170 | PubTator, text mining | PubMed |
| Discovery of tumor antigens in renal cell carcinoma and prospects for clinical application. | Front Immunol | 2026 | 41972142 | PubTator, text mining | PubMed |
| First review of chronic granulomatous disease in Palestine: clinical and genetic characteristics. | Front Immunol | 2026 | 41958672 | PubTator, text mining | PubMed |
1 to 10 of 1,992
See all 1,992 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4689
GET https://conductscience.org/api/genes/v1/4689/patents