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NUCLEOLIN: nucleolin multifunctional protein

1 protein, 68 patents, 0 drugs, 0 trials, 3,689 NIH grants and 7,232 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolNUCLEOLINHGNC
Namenucleolin multifunctional proteinHGNC
NCBI Gene ID4691NCBI Gene
HGNC IDHGNC:7667HGNC
EnsemblENSG00000115053NCBI Gene
AliasesC23, NCL, Nsr1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P19338Nucleolin7104Ensembl, GeneID, HGNCUniProt

Patents 68

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-195169P19338Espacenet
JP 2025517970 A2025-06-125169P19338Espacenet
US 12312588 B22025-05-27493P19338Espacenet
JP 2024123008 A2024-09-107464P19338Espacenet
JP 2024530931 A2024-08-2712P19338Espacenet
EP 4380580 A22024-06-1212P19338Espacenet
KR 1020240083171 A2024-06-1112P19338Espacenet
JP 2024009871 A2024-01-237P19338Espacenet
US 11860162 B22024-01-021526P19338Espacenet
JP 2023534800 A2023-08-141P19338Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3689

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant232,025NIH's project files
P30CA006973Regional Oncology Research Center162,025NIH's project files
P30CA016058Cancer Center Support Grant162,025NIH's project files
ZIAAG000511Post-transcriptional control of Proliferation, Stress Response & Carcinogenesis122,025NIH's project files
P30CA008748Cancer Center Support Grant112,025NIH's project files
P30CA021765Cancer Center Support Grant (CCSG)112,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center102,025NIH's project files
ZIAAG000393Influence of Post-transcriptional Gene Regulation on Cell Senescence and Aging92,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program72,025NIH's project files
P30CA016087Cancer Center Support Grant72,025NIH's project files

Papers 7232

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42823417PubTator, text miningPubMed
42818213PubTator, text miningPubMed
42800329PubTator, text miningPubMed
42798295PubTator, text miningPubMed
42790162PubTator, text miningPubMed
42779673PubTator, text miningPubMed
42767175PubTator, text miningPubMed
42757385PubTator, text miningPubMed
42738794PubTator, text miningPubMed
42718597PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license