ConductScience.org, home

Gene · 4700

NDUFA6: NADH:ubiquinone oxidoreductase subunit A6

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. NDUFA6: NADH:ubiquinone oxidoreductase subunit A6. Genes, record 4700. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4700

On this page

Gene

Symbol
NDUFA6
HGNC
Name
NADH:ubiquinone oxidoreductase subunit A6
HGNC
NCBI Gene ID
4700
NCBI Gene
HGNC ID
HGNC:7690
HGNC
Ensembl
ENSG00000184983
NCBI Gene
Aliases
B14, CI-B14, LYRM6, MC1DN33, NADHB14
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P56556NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 61287Ensembl, GeneID, HGNC

Source UniProt

Patents14

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1914253P56556Espacenet
JP 2025517970 A2025-06-1214253P56556Espacenet
JP 2024507735 A2024-02-21200P56556Espacenet
US 11446398 B22022-09-2055071P56556Espacenet
US 11446398 B22022-09-2055082P56556Espacenet
US 11446398 B22022-09-2055083P56556Espacenet
US 11446398 B22022-09-2055085P56556Espacenet
JP 2022524081 A2022-04-27158042P56556Espacenet
JP 2022524081 A2022-04-27158053P56556Espacenet
JP 2022524081 A2022-04-27158054P56556Espacenet

1 to 10 of 14

See all 14 patents

Drugs4

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ME-344CHEMBL5314386Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL
METFORMINCHEMBL1431Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL
METFORMIN HYDROCHLORIDECHEMBL1703Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL
NV-128CHEMBL3545135Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL

Trials1,218

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants1,046

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNDUFA6 papersNewest fiscal year
ZIAHD008814Mammalian iron-sulfur cluster biogenesis62025
P30CA008748Cancer Center Support Grant32025
P30CA010815Consolidated Basic Cancer Research Program32025
P30CA016672Cancer Center Support Grant32025
R01AI080607Studies in Poxvirus Host Range Genes and Tropism32025
T32HL007576Training in Cardiovascular Research32025
ZIAHD001602Regulation Of Intracellular Iron Metabolism32025
P20GM103408Idaho INBRE Program22025
P30AI036219Rustbelt Center for AIDS Research (Case/UHC-Pitt CFAR)22025
P30CA016087Cancer Center Support Grant22025

1 to 10 of 1,046Source NIH's project files

See all 1,046 nih grants

Papers1,297

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Identification of mitochondrial energy metabolism-related candidate genes UQCR10 and NDUFA6 in pediatric tetralogy of fallot: an exploratory bioinformatics study.J Cardiothorac Surg202642289731PubTator, text miningPubMed
No Correlation Between Interferon Signaling and Cytosolic Mitochondrial DNA/RNA Leakage in Cultured Skin Fibroblasts of Patients With Mitochondrial Diseases.Eur J Immunol202641891263PubTator, text miningPubMed
Hyaluronic acid degradation by Purpureocillium lilacinum: biochemical and transcriptomic insights.Appl Microbiol Biotechnol202641865196PubTator, text miningPubMed
Exploring Gene Expression Patterns in Alzheimer's Disease Using a Human Microarray Data Meta-Analysis.Biology (Basel)202641744654PubTator, text miningPubMed
Tuning the gate and the gear: The LRRC26 (γ1) subunit modulates intrinsic gating and voltage-sensor coupling of the BK channel.Proc Natl Acad Sci U S A202641701845PubTator, text miningPubMed
Dual-Activity Mannosyltransferase Phosphorylases in Family 130 of Glycoside Hydrolases.ACS Catal202641561435PubTator, text miningPubMed
MCD enzyme deficiency drives early mortality and multiorgan metabolic disruption in Dahl salt-sensitive rats.iScience202641550752PubTator, text miningPubMed
Integrated proteomics and metabolomics reveal phytosesquiterpene lactones inhibit TNBC cell activity by depleting ATP synthesis and reprogramming primary metabolism.Sci Rep202641530404PubTator, text miningPubMed
An Overview of Drug-Resistant Epilepsies Based on Advances in Genetics: A Cohort Study.Neurol India202641510857PubTator, text miningPubMed
Discovery of a small-molecule inhibitor of eIF4E suppressing tumor proliferation via lipid metabolic reprogramming.J Adv Res202641468962PubTator, text miningPubMed

1 to 10 of 1,297

See all 1,297 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4700

GET https://conductscience.org/api/genes/v1/4700/patents