ConductScience.org, home

Gene · 4705

NDUFA10: NADH:ubiquinone oxidoreductase subunit A10

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. NDUFA10: NADH:ubiquinone oxidoreductase subunit A10. Genes, record 4705. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4705

On this page

Gene

Symbol
NDUFA10
HGNC
Name
NADH:ubiquinone oxidoreductase subunit A10
HGNC
NCBI Gene ID
4705
NCBI Gene
HGNC ID
HGNC:7684
HGNC
Ensembl
ENSG00000130414
NCBI Gene
Aliases
CI-42KD, CI-42k, MC1DN22
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O95299NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial3556Ensembl, GeneID, HGNC

Source UniProt

Patents34

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1454916O95299Espacenet
EP 4650780 A22025-11-191407O95299Espacenet
JP 2025147176 A2025-10-069238O95299Espacenet
JP 2025529142 A2025-09-047123O95299Espacenet
US 12371689 B22025-07-297123O95299Espacenet
JP 2025517970 A2025-06-121407O95299Espacenet
JP 2025028160 A2025-02-289238O95299Espacenet
KR 1020250010750 A2025-01-219238O95299Espacenet
JP 2024109657 A2024-08-149245O95299Espacenet
US 11446398 B22022-09-2055003O95299Espacenet

1 to 10 of 34

See all 34 patents

Drugs4

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ME-344CHEMBL5314386Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL
METFORMINCHEMBL1431Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL
METFORMIN HYDROCHLORIDECHEMBL1703Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL
NV-128CHEMBL3545135Mitochondrial complex I (NADH dehydrogenase) inhibitorINHIBITORChEMBL

Trials1,218

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

NIH grants401

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNDUFA10 papersNewest fiscal year
P30CA076292Moffitt Cancer Center Support Grant22025
P40OD018537Bloomington Drosophila Stock Center at Indiana University22025
ZIAHD008967Genetic epidemiology of early growth and cardiometabolic diseases22025
K00CA264422A visible machine learning system to discover targeted treatment solutions in cancer12025
OT2OD032742Bridge2AI: Cell Maps for AI (CM4AI) Data Generation Project12025
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions12025
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.12025
P20GM121316Nebraska Center for Molecular Target Discovery and Development12025
P30AG066507Johns Hopkins Alzheimer's Disease Research Center12025
P30AG066512Alzheimer's Disease Research Center - Administrative Supplement 202512025

1 to 10 of 401Source NIH's project files

See all 401 nih grants

Papers494

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Exosomes From Cancer-Associated Fibroblasts Suppress Ferroptosis and CD8+ T Cell Effector Function in Gastric Cancer via miR-4435/NDUFA10 Axis.FASEB J202642760918PubTator, text miningPubMed
Oxidized protein states define metastatic fitness in lung cancer.bioRxiv202642523302PubTator, text miningPubMed
NDUFA10: An Emerging Oncogenic Driver of Metastasis in Lung Adenocarcinoma.Curr Cancer Drug Targets202641944119PubTator, text miningPubMed
Roles of mitochondrial complexes in non-alcoholic fatty liver disease.Front Mol Biosci202641809730PubTator, text miningPubMed
SARS-CoV-2 altered mitochondrial DNA methylation in Indian COVID-19 patients.Sci Rep202641554758PubTator, text miningPubMed
Mass Spectrometry Proteomics: A Key to Faster Drug Discovery.J Med Chem202641433248PubTator, text miningPubMed
Recessive variants in mitochondrial complex I nuclear subunits are an underrated cause of optic atrophy.Brain202641234160PubTator, text miningPubMed
Extruded Limnospira platensis with enzyme supplementation shifts the broiler muscle proteome toward enhanced energy metabolism pathways.J Proteomics202641033654PubTator, text miningPubMed
Linking Personality Traits to Mediterranean Diet Adherence and Exploring Gene-Diet Interactions in Neuroticism.Nutrients202541374081PubTator, text miningPubMed
Bronchoalveolar lavage proteomics in exacerbation of bronchiectasis.BMC Pulm Med202541034841PubTator, text miningPubMed

1 to 10 of 494

See all 494 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4705

GET https://conductscience.org/api/genes/v1/4705/patents?page=2