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Gene · 4736

RPL10A: ribosomal protein L10a

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RPL10A: ribosomal protein L10a. Genes, record 4736. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4736

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Gene

Symbol
RPL10A
HGNC
Name
ribosomal protein L10a
HGNC
NCBI Gene ID
4736
NCBI Gene
HGNC ID
HGNC:10299
HGNC
Ensembl
ENSG00000198755
NCBI Gene
Aliases
CSA19, Csa-19, L10A, NEDD6, uL1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P62906Large ribosomal subunit protein uL121769Ensembl, GeneID, HGNC

Source UniProt

Patents35

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-199396P62906Espacenet
EP 4641202 A22025-10-295605P62906Espacenet
JP 2025517970 A2025-06-129396P62906Espacenet
KR 1020250017231 A2025-02-045605P62906Espacenet
WO 2024240908 A12024-11-2837P62906Espacenet
US 11884978 B22024-01-30716P62906Espacenet
US 11860162 B22024-01-021388P62906Espacenet
US 11564998 B22023-01-315447P62906Espacenet
US 11446398 B22022-09-2073927P62906Espacenet
JP 2022524081 A2022-04-27176898P62906Espacenet

1 to 10 of 35

See all 35 patents

Drugs9

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ATALURENCHEMBL25699780S Ribosome modulatorMODULATORChEMBL
CITATUZUMAB BOGATOXCHEMBL174300080S Ribosome inhibitorINHIBITORChEMBL
CYCLOHEXIMIDECHEMBL12329280S Ribosome inhibitorINHIBITORChEMBL
DORLIMOMAB ARITOXCHEMBL210912480S Ribosome inhibitorINHIBITORChEMBL
ELX-02CHEMBL429774480S Ribosome modulatorMODULATORChEMBL
MT-3724CHEMBL429778980S Ribosome inhibitorINHIBITORChEMBL
TAPLITUMOMAB PAPTOXCHEMBL210789080S Ribosome inhibitorINHIBITORChEMBL
TELIMOMAB ARITOXCHEMBL210879080S Ribosome inhibitorINHIBITORChEMBL
ZOLIMOMAB ARITOXCHEMBL210878580S Ribosome inhibitorINHIBITORChEMBL

Trials38

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07523581ELX-02PHASE2ClinicalTrials.gov
NCT05448755ELX-02PHASE22026-02-24ClinicalTrials.gov
NCT04336826ATALURENPHASE22024-04-01ClinicalTrials.gov
NCT04135495ELX-02PHASE2ClinicalTrials.gov
NCT04126473ELX-02PHASE2ClinicalTrials.gov
NCT04117880ATALURENPHASE2ClinicalTrials.gov
NCT04069260ELX-02PHASE2ClinicalTrials.gov
NCT04014530ATALURENPHASE1/PHASE2ClinicalTrials.gov
NCT03796637ATALURENPHASE22022-04-05ClinicalTrials.gov
NCT03645395MT-3724PHASE22022-08-16ClinicalTrials.gov

1 to 10 of 38

See all 38 trials

NIH grants686

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRPL10A papersNewest fiscal year
P30CA008748Cancer Center Support Grant42025
R01HD086634Specialized Translational Control of Stem Cell Differentiation and Embryonic Development42025
P30CA016086Cancer Center Support Grant32025
P30DK034854Integrated Epithelial and Muscosal Biology32025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control32025
P01CA092584Structural Cell Biology of DNA Repair Machines22025
P30AI027763UCSF-Bay Area Center for AIDS Research22025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant22025
P30CA016672Cancer Center Support Grant22025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202822025

1 to 10 of 686Source NIH's project files

See all 686 nih grants

Papers678

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Exploration of the proxiOME of large subunit ribosomal proteins reveals Acl1 and Bcl1 as cooperating dedicated chaperones of Rpl1.Nucleic Acids Res202641909949PubTator, text miningPubMed
Mitochondrial and Ribosomal Stress Underlying Pronuclear Envelope Breakdown Failure: Insights From Single-Cell Transcriptomics in Human Zygotes.Mol Reprod Dev202641787695PubTator, text miningPubMed
Manganese modulates hepatocellular carcinoma cytotoxicity and doxorubicin sensitivity in a dose dependent manner.Front Oncol202641768239PubTator, text miningPubMed
Intraoperative Biologization of β-TCP and PCL-TCP by Autologous Proteins.J Funct Biomater202541003411PubTator, text miningPubMed
Stem loop binding protein promotes SARS-CoV-2 replication via -1 programmed ribosomal frameshifting.Signal Transduct Target Ther202540514371PubTator, text miningPubMed
Insufficiency of 40S ribosomal proteins, RPS26 and RPS25, negatively affects biosynthesis of polyglycine-containing proteins in fragile-X associated conditions.Elife202540377206PubTator, text miningPubMed
Proteomic signatures of retinal pigment epithelium-derived exosomes in myopic and non-myopic tree shrew eyes.Front Med (Lausanne)202540330779PubTator, text miningPubMed
Candidate target genes in sepsis diagnosis and therapy: identifying hub genes with a spotlight on KLRB1.BMC Infect Dis202540133824PubTator, text miningPubMed
Nanometer condensate organization in live cells derived from partitioning measurements.bioRxiv202540060647PubTator, text miningPubMed
High-throughput approaches for the identification of ribosome heterogeneity.Philos Trans R Soc Lond B Biol Sci202540045778PubTator, text miningPubMed

1 to 10 of 678

See all 678 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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