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NEDD8: NEDD8 ubiquitin like modifier
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Gene · 4738

Papers3,078

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

21 to 40 of 3,078

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TitleJournalYearPMIDFound bySource
NEDD8 Promotes the Progression and Inflammation of Keratoconus by Increasing the Expression of YAP1.Invest Ophthalmol Vis Sci202642262027PubTator, text miningPubMed
Protein Neddylation Beyond Tumor Cells is a Vital Modulator of Anticancer Immunity.Phenomics202642238031PubTator, text miningPubMed
Structure-activity relationships in a series of dihydrouracil-JQ1 conjugates: discovery of highly potent BRD4 degraders.RSC Med Chem202642232063PubTator, text miningPubMed
Identifying Neddylation-modified features to assess prognosis and immune efficacy in hepatocellular carcinoma.Apoptosis202642178458PubTator, text miningPubMed
CRL4AMBRA1-mediated progesterone receptor degradation drives progestin resistance and represents a therapeutic vulnerability in endometrial cancer.Int J Biol Sci202642157930PubTator, text miningPubMed
EXOSC4 as a novel regulator of neddylation in acute myeloid leukemia.Sci Rep202642128900PubTator, text miningPubMed
The modifier matrix: emerging roles of ubiquitin-like proteins in Alzheimer's disease.Mol Neurodegener Adv202642111249PubTator, text miningPubMed
NSUN2/ALYREF stabilizes m5C-modified circCEP70 to enhance radioresistance in rectal cancer through NEDD8-dependent neddylation and ubiquitination regulation.Int J Biol Macromol202642106046PubTator, text miningPubMed
CUL5-mediated ubiquitination in cancer cell therapy: context-dependent roles, molecular networks, and emerging therapeutic avenues.Front Med (Lausanne)202642078440PubTator, text miningPubMed
Orlistat targets NEDD8 conjugating enzyme UBC12 for cancer therapy.Pharmacol Res202642067003PubTator, text miningPubMed
Multimodal immunopharmacologic screens identify drugs rewiring the cancer-immune interface.bioRxiv202642039582PubTator, text miningPubMed
Pharmacological inhibition of host cell neddylation reduces intoxication of cells by diphtheria toxin and clostridial enterotoxins TcdB and C2.Microbiol Spectr202641925373PubTator, text miningPubMed
Ubiquitin-like modifications in adipose tissue development and obesity: New insights.Biochim Biophys Acta Mol Basis Dis202641921625PubTator, text miningPubMed
Comparative proteomics reveals protein signatures shared between and unique to bona fide plant EVs and other plant-derived vesicles.Plant Physiol202641914509PubTator, text miningPubMed
Current Insights into Clinical, Molecular, and Therapeutic Approaches to Acute Respiratory Distress Syndrome.Med Sci (Basel)202641892849PubTator, text miningPubMed
Heart failure in autoimmune rheumatic diseases.Rheumatol Int202641882329PubTator, text miningPubMed
AP39 alleviates HHCY-induced myocardial remodeling by regulating FUNDC1-mediated mitochondrial dynamics via S-sulfhydration of NEDD8/CUL4B.Front Pharmacol202641878332PubTator, text miningPubMed
In vitro cellular tropism and immunomodulatory response to rVSVΔG-ZEBOV-GP in human cells derived from tissues associated with adverse events.Microbiol Spectr202641874168PubTator, text miningPubMed
Finely-tuned regulator of DNA repair: FBXW7-185aa may modulate glioblastoma radiosensitization and the tumor immune microenvironment.Transl Oncol202641861660PubTator, text miningPubMed
FBXW7 Targets the SPT6-ΔNp63 Axis for Degradation to Inhibit Esophageal Tumorigenesis Induced by 4-Nitroquinoline N-Oxide.MedComm (2020)202641799933PubTator, text miningPubMed

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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