ConductScience.org, home

Gene · 4741

NEFM: neurofilament medium chain

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. NEFM: neurofilament medium chain. Genes, record 4741. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4741

On this page

Gene

Symbol
NEFM
HGNC
Name
neurofilament medium chain
HGNC
NCBI Gene ID
4741
NCBI Gene
HGNC ID
HGNC:7734
HGNC
Ensembl
ENSG00000104722
NCBI Gene
Aliases
NEF3, NF-M, NFM
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P07197Neurofilament medium polypeptide9160Ensembl, GeneID, HGNC

Source UniProt

Patents39

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1455432P07197Espacenet
EP 4641201 A22025-10-29347P07197Espacenet
JP 2025517969 A2025-06-12347P07197Espacenet
JP 2025032204 A2025-03-1132227P07197Espacenet
US 12247986 B22025-03-116P07197Espacenet
EP 4461818 A22024-11-1332227P07197Espacenet
JP 2024096258 A2024-07-124P07197Espacenet
KR 1020240002810 A2024-01-084P07197Espacenet
JP 2023118821 A2023-08-253P07197Espacenet
JP 2023058610 A2023-04-2532227P07197Espacenet

1 to 10 of 39

See all 39 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,223

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNEFM papersNewest fiscal year
R01NS027036Disease Mechanism and Therapy in TDP-43 Proteinopathies and Dementias82025
P30CA008748Cancer Center Support Grant52025
P51OD011092Support for National Primate Research Center42025
P30CA016672Cancer Center Support Grant32025
P30CA021765Cancer Center Support Grant (CCSG)32025
P30EY008098Core Grant for Vision Research32025
R01GM118847Cell signaling through O-GlcNAc reader proteins32025
P30AG066511Goizueta Alzheimer's Disease Research Center22025
P30AI045008Penn Center for AIDS Research22025
P30CA006973Regional Oncology Research Center22025

1 to 10 of 1,223Source NIH's project files

See all 1,223 nih grants

Papers1,719

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
[Laryngeal squamous cell carcinoma-derived exosomes promote neuronal axonal growth by remodeling the neural microenvironment].Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi202642706064PubTator, text miningPubMed
Development and validation of hypermethylated gene markers in cervical cytological samples for detecting endometrial cancer (EndoMethy-I trial).Front Oncol202642404224PubTator, text miningPubMed
Sirt1 transgene delivery improves diabetes-impaired wound healing.Bioact Mater202642327495PubTator, text miningPubMed
Chemically Defined Medium Enables GDNF-Driven Early Neuronal-like Phenotype of Human Dental Pulp Stem Cells.Cells202642193962PubTator, text miningPubMed
NEFL⁺NEFM⁺ myeloid-reprogrammed cells promote ccRCC progression through CX3CL1-CX3CR1-mediated Tregs chemotaxis.Mol Cell Biochem202642189461PubTator, text miningPubMed
Research progress in heterogeneity of dental mesenchymal stem cells.Int J Oral Sci202641932866PubTator, text miningPubMed
Multiblock proteomic profiling identifies novel biomarkers linking prediabetes with preclinical atherosclerosis in apparently healthy adults.Cardiovasc Diabetol202641904484PubTator, text miningPubMed
Cytoskeltal intermediate filaments in Tau pathology and neurodegeneration.Adv Protein Chem Struct Biol202641904009PubTator, text miningPubMed
Architects of the Developing Brain: Cytoskeleton-Organizing Molecules in Neurodevelopmental Disorders.Cells202641892327PubTator, text miningPubMed
PINCH proteins orchestrate vascular mural cell homeostasis through integrated signaling and transcriptional networks.Angiogenesis202641795751PubTator, text miningPubMed

1 to 10 of 1,719

See all 1,719 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4741

GET https://conductscience.org/api/genes/v1/4741/patents?page=2