Gene · 4741
NEFM: neurofilament medium chain
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NEFM: neurofilament medium chain. Genes, record 4741. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4741
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P07197 | Neurofilament medium polypeptide | 916 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents39
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 55432 | P07197 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 347 | P07197 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 347 | P07197 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 32227 | P07197 | Espacenet |
| US 12247986 B2 | 2025-03-11 | 6 | P07197 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 32227 | P07197 | Espacenet |
| JP 2024096258 A | 2024-07-12 | 4 | P07197 | Espacenet |
| KR 1020240002810 A | 2024-01-08 | 4 | P07197 | Espacenet |
| JP 2023118821 A | 2023-08-25 | 3 | P07197 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 32227 | P07197 | Espacenet |
1 to 10 of 39
See all 39 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,223
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NEFM papers | Newest fiscal year |
|---|---|---|---|
| R01NS027036 | Disease Mechanism and Therapy in TDP-43 Proteinopathies and Dementias | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P51OD011092 | Support for National Primate Research Center | 4 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 3 | 2025 |
| P30CA021765 | Cancer Center Support Grant (CCSG) | 3 | 2025 |
| P30EY008098 | Core Grant for Vision Research | 3 | 2025 |
| R01GM118847 | Cell signaling through O-GlcNAc reader proteins | 3 | 2025 |
| P30AG066511 | Goizueta Alzheimer's Disease Research Center | 2 | 2025 |
| P30AI045008 | Penn Center for AIDS Research | 2 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 2 | 2025 |
1 to 10 of 1,223Source NIH's project files
See all 1,223 nih grantsPapers1,719
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| [Laryngeal squamous cell carcinoma-derived exosomes promote neuronal axonal growth by remodeling the neural microenvironment]. | Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi | 2026 | 42706064 | PubTator, text mining | PubMed |
| Development and validation of hypermethylated gene markers in cervical cytological samples for detecting endometrial cancer (EndoMethy-I trial). | Front Oncol | 2026 | 42404224 | PubTator, text mining | PubMed |
| Sirt1 transgene delivery improves diabetes-impaired wound healing. | Bioact Mater | 2026 | 42327495 | PubTator, text mining | PubMed |
| Chemically Defined Medium Enables GDNF-Driven Early Neuronal-like Phenotype of Human Dental Pulp Stem Cells. | Cells | 2026 | 42193962 | PubTator, text mining | PubMed |
| NEFL⁺NEFM⁺ myeloid-reprogrammed cells promote ccRCC progression through CX3CL1-CX3CR1-mediated Tregs chemotaxis. | Mol Cell Biochem | 2026 | 42189461 | PubTator, text mining | PubMed |
| Research progress in heterogeneity of dental mesenchymal stem cells. | Int J Oral Sci | 2026 | 41932866 | PubTator, text mining | PubMed |
| Multiblock proteomic profiling identifies novel biomarkers linking prediabetes with preclinical atherosclerosis in apparently healthy adults. | Cardiovasc Diabetol | 2026 | 41904484 | PubTator, text mining | PubMed |
| Cytoskeltal intermediate filaments in Tau pathology and neurodegeneration. | Adv Protein Chem Struct Biol | 2026 | 41904009 | PubTator, text mining | PubMed |
| Architects of the Developing Brain: Cytoskeleton-Organizing Molecules in Neurodevelopmental Disorders. | Cells | 2026 | 41892327 | PubTator, text mining | PubMed |
| PINCH proteins orchestrate vascular mural cell homeostasis through integrated signaling and transcriptional networks. | Angiogenesis | 2026 | 41795751 | PubTator, text mining | PubMed |
1 to 10 of 1,719
See all 1,719 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4741
GET https://conductscience.org/api/genes/v1/4741/patents?page=2